Benefits of using RNA-seq for clinical cancer diagnostics
Short interview with Key Opinion Leader Thoas Fioretos, Professor in Clinical Genetics, Lund University, Sweden about major benefits of using RNA-seq in the clinical setting.
- Improved diagnostics workflow using whole transcriptome RNA sequencing
- Patient subtyping and risk stratification using RNA sequencing
- Gene expression subtype classification models
- Gene fusion analysis, such as finding true positives, comparison with gene fusions databases and investigation of the genetic context (i.e. in frame and out of frame).