Publications

Below is a list of articles published by our customers in scientific journals. 

High impact journals

A significant amount of the articles are published in high impact journals. 

Covering different topics and a wide range of different data types.

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Gatikrushna Panigrahi, Julián Candia, Tiffany H. Dorsey, Wei Tang, Yuuki Ohara, Jung S. Byun, Tsion Zewdu Minas, Amy Zhang, Anuoluwapo Ajao, Ashley Cellini, Harris G. Yfantis, Amy L. Flis, Dean Mann, Olga Ioffe, Xin W. Wang, Huaitian Liu, Christopher A. Loffredo, Anna Maria Napoles, and Stefan Ambs. Diabetes-associated breast cancer is molecularly distinct and shows a DNA damage repair deficiency. Link

Adnan Mansoor, Ariz Akhter, Mahboobsadat Hamidi, Tariq MahmoodRoshan, Meer-Taher Shabani-Rad and Douglas Stewart. Exploring TBL1XR1 and NCOR1 Expression in B-cell Lymphoma Subtypes: Interaction With DNA Damage Repair Genes. Anticancer Research

Nicolas Hohmann, Martin Ronald Sprick, Moritz Pohl, Azaz Ahmed, Jürgen Burhenne, Marietta Kirchner, Lucian Le Cornet, Markus Kratzmann, Jacek Hajda, Albrecht Stenzinger, Karen Steindorf, Stefan Delorme, Heinz-Peter Schlemmer, Sabine Riethdorf, Ron van Schaik, Klaus Pantel, Jens Siveke, Thomas Seufferlein, Dirk Jäger, Walter E. Haefeli, Andreas Trumpp, Christoph Springfeld. Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy. ascpt

Christina Annunziata, Kei Kudo, Yoshimi Greer, Teruhiko Yoshida, Brittney Harrington, Soumya Korrapati, Yusuke Shibuya, Leah Henegar, Jeffrey Kopp,Takeo Fujii, Stanley Lipkowitz. Dual-inhibition of NAMPT and PAK4 induces anti-tumor effects in 3D-spheroids model of platinum-resistant ovarian cancer. Research Square

Gabriel Velez, Julian Wolf, Antoine Dufour, Prithvi Mruthyunjaya, Vinit B. Mahajan. Cross-Platform Identification and Validation of Uveal Melanoma Vitreous Protein Biomarkers. iovs

Paul A De Sousa, Jinpei Ye, Kay Samuels, Ewa Piotrowska, Martin Gordon, Elsa Abranches, Thomas M Wishart, David H Dockrell, Ryan Mate. Hyaluronan in mesenchymal stromal cell lineage differentiation from human pluripotent stem cells: Application in serum free culture. Research Square

Q Guo. Bioinformatics Analysis of the Diversity of Gut Microbiota and Different Microbiota on Insulin Resistance in Diabetes Mellitus Patients. Heliyon

M.S. Varunjikar, T. Bøhn b, M. Sanden, I. Belghit, J. Pineda-Pampliega, M. Palmblad, H. Broll, A. Braeuning, J.D. Rasinger. Proteomics analyses of herbicide-tolerant genetically modified, conventionally, and organically farmed soybean seeds. Science Direct

Yanfei Wei, Guanzhang Li, Jing Feng, Fan Wu, Zheng Zhao, Zhaoshi Bao, Wei Zhang, Xiaodong Su, Jiuyi Li, Xueling Qi, Zejun Duan, Yunqiu Zhang, Sandra Ferreyra Vega, Asgeir Store Jakola, Yingyu Sun, Helena Carén, Tao Jiang & Xiaolong Fan. Stalled oligodendrocyte differentiation in IDH-mutant gliomas. Genome Medicine

Kevin W. Ng, Jesse Boumelha, Katey S. S. Enfield, Jorge Almagro, Hongui Cha, Oriol Pich, Takahiro Karasaki, David A. Moore, Roberto Salgado, Monica Sivakumar, George Young, Miriam Molina-Arcas, Sophie de Carné Trécesson, Panayiotis Anastasiou, Annika Fendler, Lewis Au, Scott T. C. Shepherd, Carlos Martínez-Ruiz, Clare Puttick, James R. M. Black, Thomas B. K. Watkins, Hyemin Kim, Seohee Shim, Nikhil Faulkner, TRACERx Consortium, CAPTURE Consortium and George Kassiotis. Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature

Jasper Iske, Bettina Wiegmann, Fabio Ius ,Evgeny Chichelnitskiy, Kristina Ludwig,Jenny F. Kühne, Anna Maria Hitz, Kerstin Beushausen, Jana Keil, Susanne Iordanidis, Sebastián V. Rojas, Wiebke Sommer, Jawad Salman, Axel Haverich, Gregor Warnecke and Christine S. Falk. Immediate majordynamic changes in the T-and NK-cell subset compositionaftercardiac transplantation. European Journal of Immunology

Atabak M. Azad, Annette Bernhard, Anne Shen, Lene Secher Myrmel, Anne-Katrine Lundebye, Laurène Alicia Lecaudey, Even Fjære, Quang Tri Ho, Harald Sveier, Karsten Kristiansen, Morten Tønsberg Limborg, Lise Madsen. Metabolic Effects of diet containing Blue Mussel (Mytilus edulis) and Blue Mussel-fed Salmon in a Mouse Model of Obesity. Science Direct

Allison B. Andraski, Sasha A. Singh, Hideyuki Higashi, Lang Ho Lee, Masanori Aikawa, and Frank M. Sacks. The distinct metabolism between large and small HDL indicates unique origins of human apolipoprotein A. JCI Insight

Konomu Dobashi. Sync Ratio and Cluster Heat Map for Visualizing Student Engagement. Springer Link

Hina Ahsan, Muhammad Asghar, Shaukat Iqbal Malik. GCSF, A Diagnostic Marker and Potential Drug Target Candidate in Glioblastoma. Research Square

Adnan Mansoor, Hamza Kamran, Ariz Akhter, Rommel Seno, Emina E. Torlakovic, Tariq Mahmood Roshan, Meer-Taher Shabani-Rad, Ghaleb Elyamany, Parham Minoo, Douglas Stewart. Identification of Potential Therapeutic Targets for Plasmablastic Lymphoma through Gene Expression Analysis: Insights into RAS and Wnt Signaling Pathways. Modern Pathology

M.S. Varunjikar. T. Bøhn, M. Sanden, I. Belghit, J. Pineda-Pampliega, M. Palmblad, H. Broll, A. Braeuning and J.D. Rasinger. Proteomics analyses of herbicide-tolerant genetically modified, conventionally, and organically farmed soybean seeds. Science Direct

Petros Christopoulos, Thibaud Prawitz, Jin-Liern Hong, Huamao M. Lin, Luis Hernandez, Shu Jin, Min Tan, Irina Proskorovsky, Jianchang Lin, Pingkuan Zhang, Jyoti D. Patel, Sai-Hong I. Ou, Michael Thomas, Albrecht Stenzinger. Indirect comparison of mobocertinib and real-world therapies for pre-treated non-small cell lung cancer with EGFR exon 20 insertion mutations. Science Direct

Susan MacLauchlan, Priyanka Kushwaha, Albert Tai, Jia Chen, Catherine Manning, Gaurav Swarnkar, Yousef Abu-Amer, Katherine A. Fitzgerald, Shruti Sharma, and Ellen M. Gravallese. STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice. PNAS

Bilal A Siddiqui, Brian F Chapin, Sonali Jindal, Fei Duan, Sreyashi Basu, Shalini S Yadav, Ai-Di Gu, Alexsandra B Espejo, Michelle Kinder, Curtis A Pettaway, John F Ward, Rebecca S S Tidwell, Patricia Troncoso, Paul G Corn, Christopher J Logothetis, Roland Knoblauch, Natalie Hutnick, Marco Gottardis, Charles G Drake, Padmanee Sharma, and Sumit K Subudhi. Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor). BMJ Journals

D.J. Vidyadhara, Mahalakshmi Somayaji, Nigel Wade, Betül Yücel, Helen Zhao, N. Shashaank, Joseph Ribaudo, Jyoti Gupta, TuKiet T. Lam, Dalibor Sames, Lois E. Greene, David L. Sulzer, Sreeganga S. Chandra. Dopamine transporter and synaptic vesicle sorting defects underlie auxilin-associated Parkinson’s disease. ScienceDirect

Xingjian Zhang. Biophysical Signatures in Cancer and Sickle Cell Disease. Yale University ProQuest

Karolina Pavic, Nikhil Gupta, Judit Domènech Omella, Rita Derua, Anna Aakula, Riikka Huhtaniemi, Juha A. Määttä, Nico Höfflin, Juha Okkeri, Zhizhi Wang, Otto Kauko, Roosa Varjus, Henrik Honkanen, Daniel Abankwa, Maja Köhn, Vesa P. Hytönen, Wenqing Xu, Jakob Nilsson, Rebecca Page, Veerle Janssens, Alexander Leitner & Jukka Westermarck. Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A. Nature Communications

Barbara Zapała, Agnieszka Kamińska, Monika Piwowar, Agnieszka Paziewska, Agnieszka Gala-Błądzińska & Ewa Ł. Stępień. miRNA Signature of Urine Extracellular Vesicles Shows the Involvement of Inflammatory and Apoptotic Processes in Diabetic Chronic Kidney Disease. Springer Link

Sylvia Nkombo Nkoula, Griselda Velez-Aguilera, Batool Ossareh-Nazari, Lucie Van Hove, Cristina Ayuso, Véronique Legros, Guillaume Chevreux, Laura Thomas, Géraldine Seydoux, Peter Askjaer and Lionel Pintard. Mechanisms of Nuclear Pore Complex disassembly by the mitotic Polo-Like Kinase 1 (PLK-1) in C. elegans embryos. bioRxiw

Dr. Sampada Kallol, Dr. Laura Martin-Sancho, Dr. Robert Morey, Dr. Omonigho Aisagbonhi, Donald Pizzo, Morgan Meads, Dr. Sumit K Chanda, and Francesca Soncin. Activation of the interferon pathway in trophoblast cells productively infected with SARS-CoV-2. Stem Cells and Development

Tetje C. van der Sluis, Guillaume Beyrend, Esmé T.I. van der Gracht, Tamim Abdelaal, Simon P. Jochems, Robert A. Belderbos, Thomas H. Wesselink, Suzanne van Duikeren, Floortje J. van Haften, Anke Redeker, Laura F. Ouboter, Elham Beyranvand Nejad, Marcel Camps, Kees L.M.C. Franken, Margot M. Linssen, Peter Hohenstein, Noel F.C.C. de Miranda, Hailiang Mei, Adriaan D. Bins, John B.A.G. Haanen, Joachim G. Aerts, Ferry Ossendorp, Ramon Arens. OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum. Cell Medicine Reports

Tyler D. P. Goralski, Conor C. Jenkins, Daniel J. Angelini, Jennifer R. Horsmon, Elizabeth S. Dhummakupt, Gabrielle M. Rizzo, Brooke L. Simmons, Alvin T. Liem, Pierce A. Roth, Mark A. Karavis, Jessica M. Hill, Jennifer W. Sekowski, Kyle P. Glover. A novel approach to interrogating the effects of chemical warfare agent exposure using organ-on-a-chip technology and multiomic analysis. PLOS ONE 

Rashid A.. Malik Z. A.; Khilnani P., Sharief J., Kadwa, R. Brusletto, B. S. Toufiq, M. Nadeem, R. Sarpal, A. Chaussabel, D. Malik R. A., Quraishi N., Benakatti G., Zaki S. A., Uddin M. J., Ogrodzki P., Shaikh M. G., Hussain S., Salah H. M., Hussain A.. In-Vitro and in-Vivovascular Endothelial Growth Factor Subtypes a & B in Severe Acute Respiratory Syndrome Pathogenesis. Read here

Mark C. Blaser, Simon Kraler, Thomas F. Lüscher and Elena Aikawa Network-Guided Multiomic Mapping of Aortic Valve Calcification. Network-Guided Multiomic Mapping of Aortic Valve CalcificationArteriosclerosis, Thrombosis, and Vascular Biology

Robert Morey, Lara Poling, Srimeenakshi Srinivasan, Carolina Martinez-King, Adanna Anyikam, Kathy Zhang-Rutledge, To Cuong, Abbas Hakim, Marina Mochizuki, Kajal Verma, Antoinette Mason, Vy Tran, Morgan Meads, Leah Lamale-Smith, Mariko Horii, Gladys A. Ramos, Peter DeHoff, Mana M. Parast, Priya Pantham, Louise C. Laurent. Discovery and Verification of Extracellular microRNA Biomarkers for Diagnostic and Prognostic Assessment of Preeclampsia at TriagemedRxiv

Farwah Iqbal, Florian Schlotter, Dakota Becker-Greene, Adrien Lupieri, Claudia Goettsch, Joshua D Hutcheson, Maximillian A Rogers, Shinsuke Itoh, Arda Halu, Lang Ho Lee, Mark C Blaser, Andrew K Mlynarchik, Sumihiko Hagita, Shiori Kuraoka, Hao Yu Chen, James C Engert, Livia S A Passos, Prabhash K Jha, Eric A Osborn, Farouc A Jaffer, Simon C Body, Simon C Robson, George Thanassoulis, Masanori Aikawa, Sasha A Singh, Abhijeet R Sonawane, Elena Aikawa. Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity. European Heart Journal

Anne Uebel, Stefanie Kewitz-Hempel, Edith Willscher, Kathleen Gebhardt, Cord Sunderkötter and Dennis Gerloff. Resistance to BRAF Inhibitors: EZH2 and Its Downstream Targets as Potential Therapeutic Options in Melanoma. Molecular Sciences

Paula Carrillo-Rodriguez, Frode Selheim, and Maria Hernandez-Valladares. Mass Spectrometry-Based Proteomics Workflows in Cancer Research: The Relevance of Choosing the Right Steps. Cancers

Xin Lei, Indu Khatri, Tom de Wit, Iris de Rink, Marja Nieuwland, Ron Kerkhoven, Hans van Eenennaam, Chong Sun, Abhishek D. Garg, Jannie Borst & Yanling Xiao. CD4+ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment. Nature Communications

Cristiana Iosef, DVM PhD, Michael J. Knauer PhD, Michael Nicholson MD, Logan R. Van Nynatten MD, Gediminas Cepinskas PhD, Sorin Draghici PhD, Victor K. M. Han MD, Douglas D. Fraser MD PhD. Plasma Proteome of Long-covid Patients Indicates Hypoxia-mediated Vasculo-proliferative Disease With Impact on Brain and Heart Function. Research Square

Juliette Bayot; Caroline Martin, Guillaume Chevreux, Jean-Michel Camadro. The adaptive response to alternative carbon sources in the pathogen Candida albicans involves a remodeling of thiol-and glutathione-dependent redox status. Biochemical Journal

Ghaleb Elyamany, Hassan Rizwan, Ariz Akhter, Mansour S. Aljabry, Sultan Alotaibi, Mohammad A. Hameed Albalawi, Meer-Taher Shabani-Rad, Tariq Mahmood Roshan and Adnan Mansoor. “Losing the Brakes”—Suppressed Inhibitors Triggering Uncontrolled Wnt/ß-Catenin Signaling May Provide a Potential Therapeutic Target in Elderly Acute Myeloid Leukemia. MPDI

Nathalie Scrima, Romain Le Bars, Quentin Nevers, Damien Glon, Guillaume Chevreux, Ahmet Civas, Danielle Blondel, Cécile Lagaudrière-Gesbert, Yves Gaudin. Rabies virus P protein binds to TBK1 and interferes with the formation of innate immunity-related liquid condensates. ScienceDirect

Sabina Enlund, Indranil Sinha, Amanda Ramilo Amor, Shahrzad Shirazi Fard, Ekaterina Pokrovskaja Tamm, Qingfei Jiang, Vanessa Lundin, Anna Nilsson, Frida Holm. Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T-cell acute lymphoblastic leukemia. Wiley

Johanna S. Qvist, Maria Scherma, Nitya Jayaram-Lindström, Walter Fratta, Denise B. Kandel, Eric R. Kandel, Paola Fadda and Philippe A. Melas. Synaptoproteomic Analysis of the Prefrontal Cortex Reveals Spatio-Temporal Changes in SYNGAP1 Following Cannabinoid Exposure in Rat Adolescence. International Journal of Molecual Sciences

Nagarjuna R Cheemarla Ph D, Amelia Hanron MPH, Joseph R Fauver Ph D, Jason Bishai BS, Timothy A Watkins BS, Anderson F Brito Ph D, Dejian Zhao Ph D, Tara Alpert Ph D, Chantal B FVogels Ph D, Prof Albert I Ko MD, Wade L Schulz MD, Prof Marie L Landry MD, Nathan D Grubaugh Ph D, David van D Ph Ddh, Ellen F Foxman MD. Nasal host response-based screening for undiagnosed respiratory viruses: a pathogen surveillance and detection study. ScienceDirect

Shahd AlZahrani, Zakia Shinwari, Ameera Gaafar, Ayodele Alaiya and Ahmed Al-Kahtani. Anti-Inflammatory Effect of Specialized Proresolving Lipid Mediators on Mesenchymal Stem Cells: An In Vitro Study. Cells

Svea Stratmann, Mattias Vesterlund, Husen M. Umer, Saeed Eshtad, Aron Skaftason, Morten Krogh Herlin, Christer Sundström, Anna Eriksson, Martin Höglund, Josefine Palle, Jonas Abrahamsson, Kirsi Jahnukainen, Monica Cheng Munthe-Kaas, Bernward Zeller, Katja Pokrovskaja Tamm, Cecilia Lindskog, Lucia Cavelier, Janne Lehtiö & Linda Holmfeldt. Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children. Nature

Mr. Jacob Sjölin, Marianne Jonsson, Ms. Charlotta Orback, Prof. Anders Oldfors, Anders Jeppson, Dr. Jane Synnergren, Victoria Rotter Sopasakis, Dr. Kristina Vukusic. Expression of stem cell niche related biomarkers at the base of the human tricuspid valve. Stem Cells and Development

Olga S.Blomberg, Lorenzo Spagnuolo, Hannah Garner, Leonie Voorwerk, Olga I.Isaeva, Ewaldvan Dyk, Noor Bakker, Myriam Chalabi, Chris Klaver, Maxime Duijst, Kelly Kersten, Marieke Brüggemann, Dorien Pastoors, Cheei-Sing Hau, Kim Vrijland, Elisabeth A.M. Raeven, Daphne Kaldenbach, Kevin Kos, Inna S. Afonina, Paulien Kaptein, Marleen Kok. IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer. Science Direct

Renumathy Dhanasekaran, Aida S. Hansen, Jangho Park, Lea Lemaitre, Ian Lai, Nia Adeniji, Sibu Kuruvilla, Akanksha Suresh, Josephine Zhang, Varsha Swamy, Dean W. Felsher. MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma that is Reversible Through Restoration of Pro-Inflammatory Macrophages. AACR Journals

Janine Dywicki, Laura Elisa Buitrago-Molina, Fatih Noyan, Jerome Schlue, Konstantinos Iordanidis, Michael P. Manns, Heiner Wedemeyer, Elmar Jaeckel & Matthias Hardtke-Wolenski. Splenectomy induces biochemical remission and regeneration in experimental murine autoimmune hepatitis. European Journal of Medical Research 

Maria de la Paz Celorio-Mancera, Rachel A. Steward, Peter Pruisscher, Agata Smialowska, Mariana Pires Braga, Niklas Janz, Christopher W. Wheat and Sören Nylin. Larval transcriptomes reflect the evolutionary history of plant-insect associations. Silverchair

Sajjad Asafa, Rahmatullah Jan, Muhammad Aaqil, Khanc Lubna, Abdul Latif Khan, Saleem Asif, Saqib Bila, Waqar Ahmad, Muhammad Waqase, Kyung-Min Kim, Ahmed AL-Harrasi, In-Jung Lee. Unraveling the mutualistic interaction between endophytic Curvularia lunata CSL1 and tomato to mitigate cadmium (Cd) toxicity via transcriptomic insights. ScienceDirect

Man Nie, Weicheng Ren, Xiaofei Ye, Mattias Berglund, Xianhuo Wang, Karin Fjordén, Likun Du, Yvonne Giannoula, Dexin Lei, Wenjia Su, Wei Li, Dongbing Liu, Johan Linderoth, Chengyi Jiang, Huijing Bao, Wenqi Jiang, Huiqiang Huang, Yong Hou, Shida Zhu, Gunilla Enblad, Mats Jerkeman, Kui Wu, Huilai Zhang, Rose-Marie Amini, Zhi-Ming Li, Qiang Pan-Hammarström. The dual role of CD70 in B-cell lymphomagenesis. Wiley Online Laboratory

Gemma Gaitskell-Phillips, Francisco E Martín-Cano, Eva Silva-Álvarez, José A Tapia, Antonio Silva, María C Gil, Cristina Ortega-Ferrusola, Fernando J Peña. Phosphoproteomics for identification of new mechanisms of cryodamage: the role of Spata18 in the control of stallion sperm functionOxford Academic

Rashid, A., Malik, Z. A, Khilnani, P., Sharief, J., Kadwa, R., Brusletto, B., Toufiq, M., Nadeem, R., Sarpal, A., Chaussabel, D., Malik, R. A., Quraishi, N., Benakatti, G., Zaki, S. A., Uddin, M. J., Ogrodzki, P., Shaikh, M. G., Hussain, S., Nawaz, A., Hussain, A.. PP126 [Infections » Sepsis]: The infant transcriptome in meningococcal septic shock: A force in precision cellular dysfunction suggesting a cytokine storm? Pediatric Critical Care Medicine

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Carl Sandén, Signe Modvig, Marianne Rissler, Kajsa Paulsson, Anders Castor, Cornelis Jan Pronk, Hanne Vibeke Marquart, Kjeld Schmiegelow, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos. Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4-Rearranged ALL. Ash Publications

Prof. Dr. med. Michael P. Manns et. al. Evaluation of intestinal epithelial organoids as in vitro model for analysing mechanisms of inflammatory bowel disease in the context of the 3RsMedizinische Hochschule Hannover

Zain Awamleh, Sanaa Choufani, Cheryl Cytrynbaum, Fowzan Alkuraya, Stephen Scherer, Sofia Fernandes, Catarina Rosas, Pedro Louro, Patricia Dias, Mariana Neves, Sergio Sousa and Rosanna Weksberg. ANKRD11 pathogenic variants and 16q24.3 microdeletions share an altered DNA methylation signature in patients with KBG syndrome. Download

Malene Broholm, Rasmus Bojesen, Mikail Gögenur, Andreas Weinberger Rosen, Sara Watt, Mustafa Bulut, Rasmus Vogelsang, Henning Quist Jensen, Adile Orhan, Ellen Bjerrum, Christina Søs Auður Andersen, Niels Pallisgaard, Thomas Litman, Jesper T. Troelsen, Ismail Gögenur. Circulating Cell-Free DNA and Systemic Inflammatory Response after Self Expandable Metal Stent for Malignant Bowel Obstruction. Fortune Journals

Rashid, A., Malik, Z. A., Khilnani, P., Sharief, J., Kadwa, R., Brusletto, B. S., Toufiq, M., Nadeem, R., Sarpal, A., Chaussabel, D., Malik, R. A., Quraishi, N., Benakatti, G., Zaki, S. A., Uddin, M. J., Ogrodzki, P., Shaikh, M. G., Hussain, S., Salah, H. M., Hussain, A. PP127 [Infections » Sepsis]: Heat Shock Transcription factor gene expression in paediatric and adult severe sepsis. Pediatric Critical Care Medicine

Mamta Amrute-Nayak, Luis Vincens Gand, Bushra Khan, Tim Holler, Ekaterini Kefalakes, Maike Kosanke, Theresia Kraft, ArnabNayak. SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy. Science Direct

Rashid A, Malik Z A, Khilnani P, Sharief J, Kadwa, R, Brusletto B S, Toufiq M, Nadeem R, Sarpal A, Chaussabel D, Malik R A,  Quraishi N, Benakatti G, Zaki S A, Uddin M J, Ogrodzki P, Shaikh M G, Hussain S, Salah H M, Hussain A. [Infections » Covid-19 / Sars-CoV-2]: In-vitro and in-vivovascular endothelial growth factor subtypes A & B in severe acute respiratory syndrome pathogenesis. Pediatric Critical Care Medicine

Rashid A, Malik Z A, Khilnani P, Sharief J, Kadwa, R, Brusletto B S, Toufiq M, Nadeem R, Sarpal A, Chaussabel D, Malik R A,  Quraishi N, Benakatti G, Zaki S A, Uddin M J, Ogrodzki P, Shaikh M G, Hussain S, Salah H M, Hussain A. [Infections » Covid-19 / Sars-CoV-2]: Vascular endothelial growth factor A and B inverse gene-expression in kawasaki disease and mis-C a clue to a counter-regulatory mechanism in pathogenesis). Pediatric Critical Care Medicine

Bo Franzén, Kristina Viktorsson, Caroline Kamali, Eva Darai-Ramqvist, Vitali Grozman, Vasiliki Arapi, Petra Hååg, Vitaliy O Kaminskyy, Per Hydbring, Lena Kanter, Sven Nyrén, Simon Ekman, Luigi De Petris, Rolf Lewensohn. Multiplex immune protein profiling of fine-needle aspirates from patients with non-small-cell lung cancer reveals signatures associated with PD-L1 expression and tumor stage. PubMed

Marci D. Brandenburg and Rolando Garcia-Milian. Librarians and Bioinformatics Communities Working Together to Advance Research and Instruction. IGI Global

Reza Zandi Shafagh, Sonia Youhanna, Jibbe Keulen,Joanne X. Shen, Nayere Taebnia, Lena C. Preiss, Kathrin Klein, Florian A. Büttner, Mikael Bergqvist, Wouter van der Wijngaart, Volker M. Lauschke. Bioengineered Pancreas–Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia. Advanced Science

Sofie Traynora, Mikkel Green, Terp, Aaraby Yoheswaran Nielsen, Per Guldberg, Mie Jakobsen, Pernille Gejl Pedersen, Odd Lilleng Gammelgaard, Christina Bøg Pedersen, Mathilde Thybo Pedersen, Sofie Rattenborg, Henrik Jørn Ditzel, Morten Frier Gjerstorff. DNA methyltransferase inhibition promotes recruitment of myeloid-derived suppressor cells to the tumor microenvironment through induction of tumor cell-intrinsic interleukin-1. ScienceDirect

Giulia Gallo, Petr Kotlik, Philippe Roingeard, Marc Monot, Guillaume Chevreux, Rainer G. Ulrich, Noël Tordo, Myriam Ermonval. Diverse susceptibilities and responses of human and rodent cells to orthohantavirus infection reveal different levels of cellular restriction. PLOS Neglected Tropical Diseases

Zlatic, SA, Duong, D, Gadalla, KKE, Murage, B, Ping, L, Shah, R, Fink, JJ, Khwaja, O, Swanson, LC, Sahin, M, Rayaprolu, S, Kumar, P, Rangaraju, S, Bird, A, Tarquinio, D, Carpenter, R, Cobb, S & Faundez, V. Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome. iScience

Qi Zhang, Rober Abdo, Cristiana Iosef, Tomonori Kaneko, Matthew Cecchini, Victor K. Han & Shawn Shun-Cheng Li. The spatial transcriptomic landscape of non-small cell lung cancer brain metastasis. Nature Communications

Bufe S, Zimmermann A, Ravens S, Prinz I, Buitrago-Molina LE, Geffers R, Woller N, Kühnel F, Talbot SR, Noyan F, Manns MP, Wedemeyer H, Hardtke-Wolenski M, Jaeckel E, Davalos-Misslitz AC. PD-1/CTLA-4 blockade leads to expansion of CD8+PD-1int TILs and results in tumor remission in experimental liver cancer. Karger

Ghabel Yamany, Nawaf Alkahayat, Omar Alsharif, Yasser Elborai, Mohammad Alshahrani,Omar Alsuhaibani. Pediatric Acute Myeloid Leukemia (AML): NOTCH1 activation influencing prognosis through Transforming Growth Factor-B (TGF-Beta) / SETBP1; Report of a Pilot Study from Saudi Arabia. ScienceDirect

Kapitolina Melkova, GennadyFrolov, Zhanna Sharoyan. Umbilical cord blood (ucb) and bone marrow (bm) as a source of natural killers (nk) for kir-alloreactive adoptive immunotherapy (kir-ai). ScienceDirect

YeweiWang, YingChen, Rolando Garcia-Milian, Jaya Prakash Golla, Georgia Charkoftaki, TuKiet T.Lam, David C.Thompson, Vasilis Vasiliou. Proteomic profiling reveals an association between ALDH and oxidative phosphorylation and DNA damage repair pathways in human colon adenocarcinoma stem cells. ScienceDirect

Thoas Fioretos, Valtteri Wirta, Lucia Cavelier, Eva Berglund, Mikaela Friedman, Michael Akhras, Johan Botling, Hans Ehrencrona, Lars Engstrand, Gisela Helenius, Therese Fagerqvist, David Gisselsson, Sofia Gruvberger-Saal, Ulf Gyllensten, Markus Heidenblad, Kina Höglund, Bo Jacobsson, Maria Johansson, Åsa Johansson, Maria Johansson Soller, Maréne Landström, Pär Larsson, Lars-Åke Levin, Anna Lindstrand, Lovisa Lovmar, Anna Lyander, Malin Melin, Ann Nordgren, Gunnel Nordmark, Paula Mölling, Lars Palmqvist, Richard Palmqvist, Dirk Repsilber, Per Sikora, Bianca Stenmark, Peter Söderkvist, Henrik Stranneheim, Tobias Strid, Craig E. Wheelock, Mia Wadelius, Anna Wedell, Anders Edsjö, Richard Rosenquist. Implementing precision medicine in a regionally organized healthcare system in Sweden. Nature 

Florian Schlotter, Marlieke F. Dietz, Lukas Stolz, Karl-Patrik Kresoja, Christian Besler, Anna Sannino, Karl-Philipp Rommel, Matthias Unterhuber, Maximilian von Roeder, Victoria Delgado, Holger Thiele, Jörg Hausleiter, Jeroen J. Bax, Philipp Lurz. Atrial Functional Tricuspid Regurgitation: Novel Definition and Impact on Prognosis. American heart association

Olin A. C., Holm A., Larsson P., Nellgård B., Dalla K., Schiöler L., Berguerand N. Changes in surfactant lipid composition 6 months after severe Covid-19World Health Organization

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Marc Descatoire, Remi Fritzen, Samuel Rotman, Genevieve Kuntzelman, Xavier Charles Leber, Stephanie Droz-Georget, Adrian J.Thrasher, Elisabetta Traggiai, Fabio Candotti. Critical role of WASp in germinal center tolerance through regulation of B cell apoptosis and diversification. Cell Reports

Christina Seitza, Anne-Laure Joly, Fang Fang, Katie Frith, Paul Gray, John Andersson. The FOXP3 full-length isoform controls the lineage-stability of CD4+FOXP3+ regulatory T cells. Clinical Immunology

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Madhushri S.Varunjikara, Ikram Belghita, Jennifer Gjerde, Magnus Palmblad, Eystein Ovelanda, Josef D.Rasingera. Shotgun proteomics approaches for authentication, biological analyses, and allergen detection in feed and food-grade insect species. Food Control

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Karin Ekström, Rossella Crescitelli, Hafsteinn Ingi Pétursson, Junko Johansson, Cecilia Lässer, Roger Olofsson Bagge. Characterization of surface markers on extracellular vesicles isolated from lymphatic exudate from patients with breast cancer. BMC Cancer

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Ilaria Giovannelli, Nadhim Bayatti, Abigail Brown, Dennis Wang, Marius Mickunas, William Camu, Jean-Luc Veyrune, Christine Payan, Cecilia Garlanda, Massimo Locati, Raul Juntas-Morales, Nicolas Pageot, Andrea Malaspina, Ulf Andreasson, Carey Suehs, Safa Saker, Christophe Masseguin, John de Vos, Henrik Zetterberg, Ammar Al-Chalabi, P. Nigel Leigh, Timothy Tree, Gilbert Bensimon, Paul R. Heath, Pamela J Shaw, Janine Kirby. Amyotrophic lateral sclerosis transcriptomics reveals immunological effects of low-dose interleukin-2. Brain Communications

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Quan Zhou, Hongyu Zhang, Zewei Wang, Han Zeng, Zhaopei Liu, Qiuren Huang, Zhiyuan Lin, Yang Qu, Ying Xiong, Jiajun Wang, Yuan Chang, Qi Bai, Yu Xia, Yiwei Wang, Li Liu, Bo Dai, Jianming Guo, Yu Zhu, Le Xu, Jiejie Xu. Poor clinical outcomes and immunoevasive contexture in interleukin‐9 abundant muscle‐invasive bladder cancer. International Journal of Cancer

Atsushi Fushimi, Hiroshi Takeyama, Toshiaki Tachibana, Yoshinobu Manome. Osteogenic cocktail induces calcifications in human breast cancer cell line via placental alkaline phosphatase expression. Nature

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Dorit Schleinitz, Kerstin Krause, Tobias Wohland, Claudia Gebhardt, Nicolas Linder, Michael Stumvoll, Matthias Blüher, Ingo Bechmann, Peter Kovacs, Martin Gericke, Anke Tönjes. Identification of distinct transcriptome signatures of human adipose tissue from fifteen depots. Nature 

Marco Pellino, Diego Hojsgaard, Elvira Hörandl, Timothy F. Sharbel. Chasing the Apomictic Factors in the Ranunculus auricomus Complex: Exploring Gene Expression Patterns in Microdissected Sexual and Apomictic Ovules. Genes

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Mattias Brofelth, Anna Isinger Ekstrand, Shashank Gour, Ronnie Jansson, My Hedhammar, Björn Elleby, Anders Kvist, Christer Wingren, Ulrika Axelsson, Carl A. K. Borrebaeck. Multiplex profiling of serum proteins in solution using barcoded antibody fragments and next generation sequencing. Nature

Sarah J. Goodman, Cheryl Cytrynbaum, Brian Hon-Yin Chung, Eric Chater-Diehl , Celine Aziz, Andrei L. Turinsky, Barbara Kellam, Melanie Keller, Jung Min Ko, Oana Caluseriu , Daria Grafodatskaya, Elizabeth McCready , Renee Perrier, Kit San Yeung, Luk Ho-Ming, Jerry Machado, Michael Brudno, D. James Stavropoulos, Stephen W. Scherer, Micheil Innes, Sau Wei Cheung, Sanaa Choufani, Rosanna Weksberg. EHMT1 pathogenic variants and 9q34.3 microdeletions share altered DNA methylation patterns in patients with Kleefstra syndrome. Journal of Translational Genetics and Genomics

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Natalia Krupenko, Sergey Krupenko, Folami Ideraabdullah, Susan Smith, Stephen Hursting. CERAMIDE SYNTHASE 6 IN METABOLIC RESPONSE TO  DIETARY FAT AND FOLIC ACID. Document

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Mariana Valente, Tatiana Pinho Resende, Diana Santos Nascimento, Odile Burlen-Defranoux, Francisca Soares-da-Silva, Benoit Dupont, Ana Cumano, Perpétua Pinto-do-Ó. Mouse HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury. PLOS Biology

Adam Stenman, Jan Zedenius, Carl Christofer Juhlin. Retrospective application of the pathologic tumor-node-metastasis classification system for pheochromocytoma and abdominal paraganglioma in a well characterized cohort with long-term follow-up. Surgery

Birgitte Bertelsen, Ida Viller Tuxen, Christina Westmose Yde, Migle Gabrielaite, Mathias Husted Torp, Savvas Kinalis, Olga Oestrup, Kristoffer Rohrberg, Iben Spangaard, Eric Santoni-Rugiu, Karin Wadt, Morten Mau-Sorensen, Ulrik Lassen, Finn Cilius Nielsen. High frequency of pathogenic germline variants within homologous recombination repair in patients with advanced cancer. Genomic Medicine

Noraidah Masir, Ariz Akhter, Tariq M Roshan, Chandramaya Sabrina Florence, Faridah Abdul-Rahman, Nor Rafeah Tumian, Phang Kean-Chang, Ghaleb Elyamany, Meer-Taher Shabani-Rad, Adnan Mansoor. Diffuse large B-cell lymphoma in Southeast Asian cohort: expression patterns of B-cell receptor (BCR) repertoire and its linkage with molecular subtypes and response to R-CHOP therapyJournal of Clinical Pathology

Mahra Nourbakhsh, Adnan Mansoor, Konstantin Koro, Qingrun Zhang, Parham Minoo. Expression Profiling Reveals Involvement of WNT Pathway in the Malignant Progression of Sessile Serrated Adenomas. Science Direct

Kirstin Hoff, Marta Lemme, Anne-Karin Kahlert, Kerstin Runde, Enrique Audain, Dorit Schuster, Jens Scheewe, Tim Attmann, Thomas Pickardt, Almuth Caliebe, Reiner Siebert, Hans-Heiner Kramer, Hendrik Milting, Arne Hansen, Ole Ammerpohl, Marc-Phillip Hitz. DNA methylation profiling allows for characterization of atrial and ventricular cardiac tissues and hiPSC-CMs. Clinical Epigenetics

Kelvin H. M. Kwok, Mikael Rydén, Daniel P. Andersson, Gallic Beauchef,Christelle Guere, Katell Vie, Otto Bergman, Veroniqa Lundbäck, Peter Arner, Ingrid Dahlman. Prospective analyses of white adipose tissue gene expression in relation to long-term body weight changes. International Journal of Obesity 

Lili Yu, Kai-yuan Ji, Jian Zhang, Yanxia Xu, Yue Ying, Taoyi Mai, Shuxiang Xu, Qian-bing Zhang, Kai-tai Yao, Yang Xu. Core pluripotency factors promote glycolysis of human embryonic stem cells by activating GLUT1 enhancer. Protein Cell

Adriana Bozzi, Nazish Sayed, Elena Matsa, Gabriele Sass, Evgenios Neofytou, Karl V. Clemons, Rodrigo Correa-Oliveira, David A. Stevens, and Joseph C. Wu. Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection. Research Gate

Anna Zychlinsky Scharff, Matthieu Rousseau, Livia Lacerda Mariano, Tracy Canton, Camila Rosat Consiglio, Matthew L Albert, Magnus Fontes, Darragh Duffy, Molly A Ingersoll. Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection. Pastuer

Belghit, Ikram, Lock, Erik-Jan, Fumière, Olivier, Lecrenier, Marie-Caroline, Renard, Patricia, Dieu, Marc, Berntssen, Marc H G, Palmblad, Magnus, Rasinger, Josef D. Species-Specific Discrimination of Insect Meals for Aquafeeds by Direct Comparison of Tandem Mass Spectra. Université de NAMUR

Adriana Bozzi, Nazish Sayed, Elena Matsa, Gabriele Sass, Evgenios Neofytou, Karl V.Clemons, Rodrigo Correa-Oliveira, David A.Stevens, Joseph C.Wu. Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as a Model to Study Trypanosoma cruzi Infection. Stem Cell Report

Maria T. Grinde, Bylgja Hilmarsdottir, Hanna Maja Tunset, Ida Marie Henriksen, Jana Kim, Mads H. Haugen, Morten Beck Rye, Gunhild M. Mælandsmo, Siver A. Moestue. Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer. Biomedcentral

Johanna Egelkamp, Evgeny Chichelnitskiy, Jenny F. Kühne, Franziska Wandrer, Kerstin Daemen, Jana Keil, Jan Hinrich Bräsen, Jessica Schmitz, Ramon Bellmàs‐Sanz, Susanne Iordanidis, Katherina Katsirntaki. Back signaling of HLA class I molecules and T/NK cell receptor ligands in epithelial cells reflects the rejection‐specific microenvironment in renal allograft biopsies. American Journal of  Transplantation

Kevin Hake, Ali Akhdar, Christine Neudörfl, Hermann Haller, Cornelia Blume, Christine S. Falk. Back signaling of HLA class I molecules and T/NK cell receptor ligands in epithelial cells reflects the rejection‐specific microenvironment in renal allograft biopsies. American Journal of Transplantation

Tim Lindberg, Andy Forreryd, Ola Bergendorff, Malin Lindstedt, Kathrin S.Zeller. In vitro assessment of mechanistic events induced by structurally related chemical rubber sensitizers. Science Direct

Karim H. Saba MSc, Louise Cornmark PhD, Marianne Rissler MSc, Thoas Fioretos MD PhD, Kristina Åström MD PhD, Felix Haglund MD PhD,Andrew E. Rosenberg MD, Otte Brosjö MD PhD, Karolin H. Nord PhD. Genetic profiling of a chondroblastoma‐like osteosarcoma/malignant phosphaturic mesenchymal tumor of bone reveals a homozygous deletion of CDKN2A, intragenic deletion of DMD and a targetable FN1‐FGFR1 gene fusion. Online Library

Lindsey A. Burnett, Marianna Alperin, Francesca Sesillo Boscolo, Ms. Michelle Wong, Louise C. Laurent. Uncovering Changes in Proteomic Signature of Rat Pelvic Floor Muscles in Pregnancy. The American Journal of Obstetrics and Gynecology

D. Sinkeviciute, C. Porcelli, A. Aspberg, P. Onnerfjord, A.-C. Bay-Jensen. Characterization of the IL-17 effect on articular cartilage in a translational model. An explorative study. Osteoarthritis and Cartilage 

E. Folkesson, A. Turkiewicz, V. Hughes, N. Ali, J. Tjörnstrand, P. Önnerfjord, M. Englund. Mapping the protein distribution in zones of the healthy human medial meniscus body. Osteoarthritis and Cartilage 

Martin S. Staege, Alexander Emmer. Endogenous viral elements – links between autoimmunity and cancer? Frontiers

Imen Belgacem, Sonia Pangallo, Ahmed Abdelfattah, Flora V. Romeo, Santa O. Cacciola, Maria G. Li Destri Nicosia, Gabriele Ballistreri, Leonardo Schena. Transcriptomic Analysis of Orange Fruit Treated with Pomegranate Peel Extract (PGE). PLANTS

Anastasia Meshcheryakovaa, Martin Svobodaa, Markus Jaritzb, Felicitas Mungenasta, Martina Salzmanna, Dietmar Pilsc, Dan Cacsire Castillo-Tongd, Gudrun Hagere, Andrea Wolfd, Elena Ioana, Braicuf Jalid Sehoulif, Sandrina LambrechtsgIgnace Vergoteg, Sven Mahnerh, Peter Birneri, Philip Zimmermannj, David N.Brindleyk, Georg Heinzec, Diana Mechtcheriakovaa. Interrelations of Sphingolipid and Lysophosphatidate Signaling With Immune System in Ovarian Cancer. Science Direct

Pingting Zhou, Yanyan Li, Bo Li, Meichao Zhang, Yuanhua Liu, Yuan Yao, Dong Li. NMIIA promotes tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway and EMT in pancreatic cancer. Nature Research

Christopher G. Németh, Christoph Röcken, Reiner Siebert, Jörg Wiltfang, Ole Ammerpohl, Volker Gassling. Recurrent chromosomal and epigenetic alterations in oral squamous cell carcinoma and its putative premalignant condition oral lichen planus. PLOS org

Vidal Yucha, Sarah E.Development of a complex, full thickness, in vitro human skin tissue with neuronal and immune components. ProQuest

Srimeenakshi Srinivasan, Ashish Yeri Pike, See Cheah, Allen Chung, Kirsty Danielson, Peter De Hoff, Justyna Filant, Clara D. Laurent, Lucie D. Laurent, Rogan Magee, Courtney Moeller, Venkatesh L.Murthy, Parham Nejad, Anu Paul, Isidore Rigoutsos, Rodosthenis Rodosthenous, Ravi V.Shah, Bridget Simonson, Louise C.Laurent. Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation. CellPress

Deborah R. Boone, Harris A. Weisz, Hannah E. Willey, Karen E. O. Torres, Michael T. Falduto, Mala Sinha, Heidi Spratt, Ian J. Bolding, Kathea M. Johnson, Margaret A. Parsley, Douglas S. DeWitt, Donald S. Prough, Helen L. Hellmich. Traumatic brain injury induces long-lasting changes in immune and regenerative signaling. PLOS

Wei Xu, Dylan E. Cherrier, Sylvestre Chea, Christian Vosshenrich, Nicolas Serafini, Maxime Petit, Pentao Liu, Rachel Golub, James P.Di Santo. An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials. Immunity

Sarah I. Landau, Xiaojia Guo, Heino Velazquez, Richard Torres, Eben Olson, Rolando Garcia-Milian, Gilbert W. Moeckel, Gary V. Desir, Robert Safirstein. Regulated necrosis and failed repair in cisplatin-induced chronic kidney disease. Kidney International

Ziad Al Nabhani, Sophie Dulauroy, Rute Marques, Clara Cousu, Shahed Al Bounny, François Déjardin, Tim Sparwasser, Marion Bérard, Nadine Cerf-Bensussan, Gérard Eberl. A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult. CellPress

Sergi Aranda, Anna Alcaine-Colet, Enrique Blanco, Eva Borràs, Claire Caillot, Eduard Sabidó, Luciano Di Croce. Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation. Science Advances

H. L. Smith, A. Stevens, B. Minogue, S. Sneddon, L. Shaw, L. Wood, T. Adeniyi, H. Xiao, P. Lio, S. J. Kimber, D. R. Brison. Systems based analysis of human embryos and gene networks involved in cell lineage allocation. BMC Genomics

Marion Chapellier, Pablo Peña-Martínez, Ramprasad Ramakrishnan, Mia Eriksson, Mehrnaz Safaee-Talkhoncheh, Christina Orsmark Pietras, Henrik Lilljebjörn, Carl Högberg, Anna Hagström-Andersson, Thoas Fioretos, Jonas Larsson, Marcus Järås. Arrayed Molecular Barcoding Identifies TNFSF13. As A Positive Regulator Of Acute Myeloid Leukemia-Initiating Cells. Haematologica

Christian Fougner, Helga Bergholtz, Raoul Kuiper, Jens Henrik Norum, Therese, Sørlie. Claudin-low-like mouse mammary tumors show distinct 3 transcriptomic patterns uncoupled from genomic drivers. BioRxiv, 2019

Yongjun Sui, George K. Lewis, Yichuan Wang, Kurt Berckmueller, Blake Frey, Amiran Dzutsev, Diego Vargas-Inchaustegui, Venkatramanan Mohanram, Thomas Musich, Xiaoying Shen, Anthony DeVico, Timothy Fouts, David Venzon, James Kirk, Robert C. Waters, James Talton, Dennis Klinman, John Clements, Georgia D. Tomaras, Genoveffa Franchini, Marjorie Robert-Guroff, Giorgio Trinchieri, Robert C. Gallo and Jay A. Berzofsky. Mucosal vaccine efficacy against intrarectal SHIV is independent of anti-Env antibody response The Journal of Clinical Investigation

Ying Chena, Srujana Gollab, Rolando Garcia-Milianc, David C.Thompsond, Frank J.Gonzalezb, Vasilis Vasilioua. Hepatic metabolic adaptation in a murine model of glutathione deficiency. Chemico-Biological Interactions

Shahnaz Anne Vinta Fard .The Effect of Maternal Vitamin B12 Status in Combination with High Folate Status on Gene- specific DNA Methylation in Cord Blood Mononuclear Cells. ProQuest

Céline Cousin, Marine Oberkampf, Tristan Felix, Pierre Rosenbaum, Robert Weil, Sylvie Fabrega, Valeria Morante, Donatella Negri, Andrea Cara, Gilles Dadaglio, Claude Leclerc. Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses. Cell Reports

S Notararigo, J E Viñuela Roldán, M Abanades-Tercero, J E Dominguez-Munoz, M Barreiro-de Acosta. P062 Differences in immune cell population subsets in inflammatory bowel disease patients under anti-TNF treatment. Journal of Crohn's and Colitis

Rebecca Sian Lawson. The pancreatic β-cell zinc response to chronic stimulation and extracellular zinc depletionKing's College London 

Mariana Valente, Tatiana Pinho Resende, Diana Santos Nascimento, Odile Burlen-Defranoux, Benoit Dupont, Ana Cumano, Perpetua Pinto-do-O.HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury. Biorxiv 

Francesco Nicoli, Laura Papagno, Justin J. Frere, Mariela Pires Cabral-Piccin, Emmanuel Clave, Emma Gostick, Antoine Toubert, David A. Price, Antonella Caputo, Victor Appay. Frontiers in Immunology

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Sarah E. Vidal Yucha, Kasey A. Tamamoto, Hanh Nguyen, Dana M. Cairns, David L. Kaplan. Human Skin Equivalents Demonstrate Need for Neuro‐Immuno‐Cutaneous System. Advanced Biosystems

Testoni Barbara, Lebossé Fanny, Scholtes Caroline, Berb Françoise, Miaglia Clothilde, Subic Miroslava, Loglio Alessandro, Facchetti Floriana, Lampertico Pietro, Levrero Massimo, Zoulim Fabien. Serum Hepatitis B core-related antigen (HBcrAg) correlates with covalently-closed circular DNA transcriptional activity in chronic hepatitis B patients. Journal of Hepatology

Carin Ru Shan Siowa, Denyse Shuwen Tanga, Paul Wan Sia Henga, Lai Wah Chana. Probing the impact of HPMC viscosity grade and proportion on the physical properties of co-freeze-dried mannitol-HPMC tableting excipients using multivariate analysis methods. International Journal of Pharmaceutics

Mania Ackermann, Henning Kempf, Miriam Hetze, Christina Hesse, Anna Rafiei Hashtchin, Kerstin Brinkert, Juliane Wilhelmine Schott, Kathrin Haake, Mark Philipp Kühnel, Silke Glage, Constanca Figueiredo, Danny Jonigk, Katherina Sewald, Axel Schambach, Sabine Wronski, Thomas Moritz, Ulrich Martin, Robert Zweigerdt, Antje Munderm, Nico Lachmann. Bioreactor-based mass production of human iPSCderived macrophages enables immunotherapies against bacterial airway infectionNature Communications

Günaj Rakipovski PhD, Bidda Rolin DVM, Jane Nøhr PhD, Ib Klewe PhD, Klaus S. Frederiksen PhD, Robert Augustin PhD, Jacob Hecksher-Sørensen PhD, Camilla Ingvorsen PhD, Joseph Polex-Wolf PhD, Lotte Bjerre Knudsen DMS. The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis in ApoE−/− and LDLr−/− Mice by a Mechanism That Includes Inflammatory Pathways. JACC: Basic to Translational

Xuzhang Lu, Fan Xiaolong, Jia Zhuxia, He Jinyuan and Cai Xiaohui. Predicting Treatment Response and Survival of Multiple Myeloma with the Xbp-1 Co-Expression Gene Module. Blood

Lydie Morel, Yuqin Men, Ming S. R. Chiang, Yang Tian, Shijie Jin, Julia Yelick, Haruki Higashimori, Yongjie Yan. Intracortical astrocyte subpopulations defined by astrocyte reporter Mice in the adult brain. Glia                                                                   

Daniela Weiskopf and Alessandro Sette Vijayanand, Eva Harris, Andrew K. Falconar, Esper Kallas, M. de Silva, Michael Busch, Bjoern Peters, Pandurangan Durbin, Michael J. Ricciardi, Julie E. Ledgerwood, Aravinda Mars Stone, Phillip J. Norris, Claudia M. E. Romero, Anna de Silva, Lakshmanane Premkumar, Matthew H. Collins, Sandy L. Rosales, Grégory Seumois, John Sidney, Aruna D. Alba Grifoni, Priscilla Costa-Ramos, John Pham, Yuan Tian. Cutting Edge: Transcriptional Profiling Reveals Multifunctional and Cytotoxic Antiviral Responses of Zika Virus - Specific CD8 T Cells. The Journal of Immunology

Souren Mkrtchian, Kian Leong Lee, Jessica Kåhlin, Anette Ebberyd, Lorenz Poellinger, Malin Jonsson Fagerlund, Lars I. Eriksson. Hypoxia Regulates MicroRNA Expression in the Human Carotid Body. Arterial Chemoreceptors

Omid Madadi-Sanjani, Joachim F.Kuebler, Stephanie Dippel, Anna Gigina, Christine S.Falk, Gertrud Vieten, Claus Petersen, Christian Klemanna. Long-term outcome and necessity of liver transplantation in infants with biliary atresia are independent of cytokine milieu in native liver and serum. Cytokine

Julia Vogt, Rabea Wagener, Manuel Montesinos‐Rongen, Ole Ammerpohl, Werner Paulus, Martina Deckert, Reiner Siebert. Array‐based profiling of the lymphoma cell DNA methylome does not unequivocally distinguish primary lymphomas of the central nervous system from non‐CNS diffuse large B‐cell lymphomas. Genes, Chromosomes and Cancer 

Linda Holmquist Mengelbier, Simon Lindell‐Munther, Hiroaki Yasui, Caroline Jansson, Javanshir Esfandyari, Jenny Karlsson, Kimberly Lau, Chi‐chung Hui, Daniel Bexell, Sevan Hopyan, David Gisselsson. The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis. The Journal of Pathology

James P. Bennett, Jr. and Paula M. Keeney. RNA Sequencing of Parkinson’s Ventral Midbrain to Estimate Gene Expression Reveals Marked Heterogeneity and GADD45A as a Potential Therapeutic Target. Neurodegeneration Therapeutics

Yun-Ruei Kao, Jiahao Chen, Swathi-Rao Narayanagari, Tihomira I. Todorova, Maria M. Aivalioti, Mariana Ferreira, Pedro M. Ramos, Celine Pallaud, Ioannis Mantzaris, Aditi Shastri, James B. Bussel, Amit Verma, Ulrich Steidl, Britta Will. Thrombopoietin receptor–independent stimulation of hematopoietic stem cells by eltrombopag. Science Translational Medicine

Ougaard, Sembach, Kvist, Tonnesen, Frederiksen, Egfjord. Jensen, Galsgaard. Temporal Regulation of Glomerular and Cortical Tubulointerstitial Genes Involved in the Development of Nephrotoxic Serum Nephritis. nephron

Younghyun Lee, Monica Pujol Canadell, Igor Shuryak, Jay R. Perrier, Maria Taveras, Purvi Patel, Antonius Koller, Lubomir B. Smilenov, David J. Brenner, Emily I. Chen, Helen C. Turner. Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model. Nature Scientific reports

Danielle Ahn, Matthew Wickersham , Sebastian Riquelme , Alice Prince. The Effects of IFN-λ on Epithelial Barrier Function Contribute to K. pneumoniae ST258 Pneumonia. ATS Journals 

A. Ljungars, L. Mårtensson, J. Mattsson, M. Kovacek, A.Sundberg, U-C. Tornberg, B. Jansson, N. Persson, V. Kuci Emruli, S. Ek, M. Jerkeman, M. Hansson, G. Juliusson, M. Ohlin, B. Frendéus, I. Teige & M. Mattsson. A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia. npj Precision Oncology

Yuan Li, Christoffer Soendergaard, Fredrik Holmberg Bergenheim, David M.Aronoff, Ginger Milne, Lene Buhl Riis, Jakob Benedict Seidelin, Kim B.Jensen, Ole Haagen Nielsen. COX-2–PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis. EBioMedicine

Spyridon Megremis , Katarzyna Niespodziana , Clarissa Cabauatan , Paraskevi Xepapadaki , Marek L Kowalski , Tuomas Jartti , Claus Bachert , Susetta Finotto , Peter West , Sofia Stamataki , Anna Lewandowska-Polak. Rhinovirus Species-Specific Antibodies Differentially Reflect Clinical Outcomes in Health and Asthma. ATS Journals 

Ikram Belghit, Josef D. Rasinger, Svenja Heesch, Irene Biancarosa, Nina Liland, Bente Torstensen, Rune Waagbø, Erik-Jan Lock, Christian G. Bruckner. In-depth metabolic profiling of marine macroalgae confirms strong biochemical differences between brown, red and green algae. Algal Research

Adele Mucci, Elena Lopez- Rodriguez, Miriam Hetzel, Serena Liu, Takuji Suzuki, Christine Happle, Mania Ackermann, Henning Kempf, Roman Hillje, Jessica Kunkiel, Ewa Janosz, Sebastian Brennig, Silke Glage, Jens P.Bankstahl, Sabine Dettmer, Thomas Rodt, Gudrun Gohring, Bruce Trapnell, Gesine Hansen, Cole Trapnell, Lars Knudsen, Nico Lachmann, Thomas Moritz. iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice. Cell Press

Laura E. Ratcliffe, Irina Vázquez Villaseñor, Luke Jennings, Paul R.Heath, Heather Mortiboys, Aurelie Schwartzentruber, Evangelia Karyka, Julie E. Simpson, Paul G. Ince, Claire J. Garwood, Stephen B.Wharton. Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons. Neuroscience 

Nga Thi Phan, Meriadeg Ar Gouilh, Juliette Paireau, Loan Phuong Do,  Justine Cheval, Nghia Duy Ngu, Charles Hébert, Tuan Hai Nguyen, Olivier Lortholary, Laura Tondeur, Jean-Claude Manuguerra, Robert Barouki, Johannes Sander, Nils Janzen, Hien Tran Nguyen, Paul T. Brey, Arnaud Fontanet, Marc Eloit. Hypoglycemic Toxins and  Enteroviruses as Causes  of Outbreaks of Acute Encephalitis-Like Syndrome in  Children, Bac Giang Province, Northern Vietnam. Emerging Infectious Diseases 
 

Solomon Owusu Sekyere, Bernhard Schlevogt, Friederike Mettke , Mohammad Kabbani, Katja Deterding, Thomas Christian Wirth, Arndt Vogel, Michael Peter Manns, Christine Susanne Falk, Markus Cornberg, Heiner Wedemeyer. HCC Immune Surveillance and Antiviral Therapy of Hepatitis C Virus Infection. Karger

Shahnaz Anne Vinta Fard. The Effect of Maternal Vitamin B12 Status in Combination with High Folate Status on Gene- Specific DNA Methylation in Cord Blood Mononuclear Cells. University of Toronto 

Tinhinane Fali,  Véronique Fabre-Mersseman,  Takuya Yamamoto, Charles Bayard,  Laura Papagno,  Solène Fastenackels,  Rima Zoorab, Richard A. Koup, Jacques Boddaert, Delphine Sauce, and Victor Appay. Elderly human hematopoietic progenitor cells express cellular senescence markers and are more susceptible to pyroptosis. JCI Insight 

E.M. Matz, L.D. Dou, Y.Z. Zhang, R.T. Terlecki, A.A. Atala, J.J. Jackson. 322 Stem cell conditioned media profiles and potential uses in erectile dysfunction. The Journal of Sexual Medicine 

S.W. Lee, M.R. Chae, S.J. Kang, D.H. Han, H.H. Sung, J.D. Chung, C.I. Choi, Y.H. Choi, B.R. Choi, J.K. Park. 324 Characterization and functional roles of Kv7 Channels in corpus cavernosum smooth muscle. The Journal of Sexual Medicine 

Kristina B. V. Døssing, Christina Kjær, Jonas Vikeså, Tina Binderup, Ulrich Knigge, Michael D. Culler, Andreas Kjær, Birgitte Federspiel and Lennart Friis-Hansen. Somatostatin Analogue Treatment Primarily Induce miRNA Expression Changes and Up-Regulates Growth Inhibitory miR-7 and miR-148a in Neuroendocrine Cells. Genes

Sebastian Marwitz, Lena Heinbockel, Swetlana Scheufele, Christian Kugler, Martin Reck, Klaus F. Rabe, Sven Perner, Torsten Goldmann, Ole Ammerpohl. Fountain of youth for squamous cell carcinomas? On the epigenetic age of NSCLC and corresponding tumor‐free lung tissues. International Journal Of Cancer 

Ruby Alonso, Héloïse Flament, Sébastien Lemoine, Christine Sedlik, Emanuel Bottasso, Isabel Péguillet, Virginie Prémel, Jordan Denizeau, Marion Salou, Aurélie Darbois, Nicolás Gonzalo Núñez, Benoit Salomon, David Gross, Eliane Piaggio & Olivier Lantz. Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node. Nature communications

Yongjun Sui, Amiran Dzutsev, David Venzon, Blake Frey, Vishal Thovarai, Giorgio Trinchieri & Jay A. Berzofsky. Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques. Nature MucosalImmunology

Peter Arner, Daniel P.Andersson, Jesper Bäckdahl, Ingrid Dahlman, Mikael Rydén. Weight Gain and Impaired Glucouse Metabolism in Women Are Predicted by Inefficient Subcutaneous Fat Cell Lipolysis. Cell Metabolism 

Annette Bernhard, Josef D.Rasinger, Helene Wisløff, Øyvor Kolbjørnsen, Lene Secher Myrmel, Marc H.G.Berntssen, Anne-Katrine Lundebye, Robin Ørnsrud, Lise Madsen. Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice. Food and Chemical Toxicology 

Fekadu Yadetie, Xiaokang Zhang, Eileen Marie Hanna, Libe Aranguren Abadía, Marta Eide, Nello Blaser, Morten Brun, Inge Jonassen, Anders Goksøyr, Odd André Karlsen. RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. Aquatic Toxicology 

Marine Oberkampf, Camille Guillerey, Juliette Mouriès, Pierre Rosenbaum, Catherine Fayolle, Alexandre Bobard, Ariel Savina, Eric Ogier-Denis, Jost Enninga, Sebastian Amigorena, Claude Leclerc & Gilles Dadaglio. Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells. Nature communications 

Sumihiko Hagita, Maximillian A. Rogers, Tan Pham, Jennifer R. Wen, Andrew K. Mlynarchik, Masanori Aikawa & Elena Aikawa. Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin. Nature Scientific Reports 

Carolina Tropini, Eli Lin Moss, Bryan Douglas Merrill, Ami Siddharth Bhatt, Kerwyn Casey Huang, Justin Laine Sonnenburg. Transient Osmotic Perturbation Causes Long-Term Alteration to the Gut Microbiota. Cell Press

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Walderik W. Zomerman, Sabine L.A. Plasschaert, Siobhan Conroy, Frank J. Scherpen, Tiny G.J. Meeuwsen-de Boer, Harm J. Lourens, Sergi Guerrero Llobet, Marlinde J. Smit, Lorian Slagter-Menkema, Annika Seitz, Corrie E.M. Gidding, Esther Hulleman, Pieter Wesseling, Lisethe Meijer, Leon C. van Kempen, Anke van den Berg, Daniël O. Warmerdam, Frank A.E. Kruyt, Floris Foijer, Marcel A.T.M. van Vugt, Wilfred F.A. den Dunnen, Eelco W. Hoving, Victor Guryev, Eveline S.J.M. de Bont, Sophia W.M. Bruggeman. Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma. Cell Reports 

Steven M. Kornblau, Peter P. Ruvolo, Rui-Yu Wang, V. Lokesh Battula, Elisabeth J. Shpall, Vivian R. Ruvolo, Teresa McQueen, YiHua Qui, Zhihong Zeng, Sherry Pierce, Rodrigo Jacamo, Suk-Young Yoo, Phuong M. Le, Jeffery Sun, Numsen Hail, Marina Konopleva, Michael Andreeff. Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival. EHA 

Rebeqa Gunnarsson, Sebastian Dilorenzo, Kristina B Lundin-Ström, Linda Olsson, Andrea Biloglav, Henrik Lilljebjörn, Marianne Rissler, Per Wahlberg, Anders Lundmark, Anders Castor, Mikael Behrendtz, Thoas Fioretos, Kajsa Paulsson, Anders Isaksson & Bertil Johansson. Mutation, methylation, and gene expression profiles in dup(1q)-positive pediatric B-cell precursor acute lymphoblastic leukemia. Nature Leukemia 

Rolando Garcia-Milian. Interview Transcripts Data: Data Challenges of Biomedical Researchers in the Age of Omics. Yale University 

Kai K. Lie, Ole K. Tørresen, Monica Hongrø Solbakken, Ivar Rønnestad, Ave Tooming-Klunderud, Alexander J. Nederbragt, Sissel Jentoft and Øystein Sæle. Loss of stomach, loss of appetite? Sequencing of the ballan wrasse (Labrus bergylta) genome and intestinal transcriptomic profiling illuminate the evolution of loss of stomach function in fish. BMC Genomics 

Ziqing Chen, Tea Dodig-Crnković, Jochen M. Schwenk, Sheng-ce Tao. Current applications of antibody microarrays. Clinical Proteomics 

Silvia Escudero, Elma Zaganjor, Susan Lee, Christopher P.Mill, Ann M.Morgan, Emily B.Crawford, Jiahao Chen, Thomas E.Wales, Rida Mourtada, James Luccarelli, Gregory H.Bird, Ulrich Steidl, John R.Engen, Marcia C.Haigis, Joseph T.Opferman, Loren D.Walensky. Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD. CellPress

Huan He, Indranil Sinha, Rongrong Fan, Lars-Arne Haldosen, Feifei Yan, Chunyan Zhao & Karin Dahlman-Wright. c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer. Nature Oncogene

Giulia Fregnia, Mathieu Quinodozb, Emely Möllera, Joanna Vuillea, Sabine Gallanda, Carlo Fuscoa, Patricia Martina, Igor Letovaneca, Paolo Proveroc, Carlo Rivoltab, Nicolo Riggia, Ivan Stamenkovica. Reciprocal modulation of mesenchymal stem cells and tumor cells promotes lung cancer metastasis. EBiomedicine

Wang Zhang, Anoop T.Ambikan, Maike Sperk, Robert van Domselaar, Piotr Nowak, Kajsa Noyan, Aman Russom, Anders Sönnerborg, Ujjwal Neogi. Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers. EBioMedicine

Marcus D. Goncalves, Seo-Kyoung Hwang, Chantal Pauli, Charles J. Murphy, Zhe Cheng, Benjamin D. Hopkins, David Wu, Ryan M. Loughran, Brooke M. Emerling, Guoan Zhang, Douglas T. Fearon and Lewis C. Cantley. Fenofibrate prevents skeletal muscle loss in mice with lung cancer. PNAS 

Hanif Esmail, Rachel P. Lai, Maia Lesosky, Katalin A. Wilkinson, Christine M. Graham, Stuart Horswell, Anna K. Coussens, Clifton E. Barry, Anne O’Garra and Robert J. Wilkinson. Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis. PNAS 

Francesca Soncin, Marwa Khater, Cuong To, Donald Pizzo, Omar Farah, Anna Wakeland, Kanaga Arul Nambi Rajan, Katharine K. Nelson, Ching-Wen Chang, Matteo Moretto-Zita, David R. Natale, Louise C. Laurent, Mana M. Parast. Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development. Development 

Nathan L. Price, Abhishek K. Singh, Noemi Rotllan, Leigh Goedeke, Allison Wing, Alberto Canfrán-Duque, Alberto Diaz-Ruiz, Elisa Araldi, Ángel Baldán, Joao-Paulo Camporez, Yajaira Suárez, Matthew S. Rodeheffer, Gerald I. Shulman, Rafael de Cabo, Carlos Fernández-Hernando. Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance. Cell Reports

Shirin Elizabeth Khorsandi, Siamak Salehi, Miriam Cortes, Hector Vilca-Melendez, Krishna Menon, Parthi Srinivasan, Andreas Prachalias, Wayel Jassem & Nigel Heaton. An in silico argument for mitochondrial microRNA as a determinant of primary non function in liver transplantation. Nature Scientific reports 

Vasiliki Pelekanoua, Eleftheria Anastasioub, Efstathia Bakogeorgoub, George Notasb, Marilena Kampab, Rolando Garcia-Miliand, Katerina Lavredakib, Eleni Moustoua, Georgia Chinarie, Petroula Arapantonie, Anthony O'Gradyf, Vassilios Georgouliash, Andreas Tsapisb, Efstathios N. Stathopoulosa, Elias Castanasb. Estrogen receptor-alpha isoforms are the main estrogen receptors expressed in non-small cell lung carcinoma. Steroids

Glaesener S, Jaenke C, Habener A, Geffers R, Hagendorff P, Witzlau K, Imelmann E, Kreuger Andreas, Meyer-Bahlburg A. Decreased production of class-switched antibodies in neonatal B cells is associated with increased expression of miR-181b. PLOS One

Sperk M, Zhang W, Nowak P, Neogi U. Plasma soluble factor following two decades prolonged suppressive antiretroviral therapy in HIV-1-positive males: A cross-sectional study. NCBI 

Veena S. Patil, Ariel Madrigal, Benjamin J. Schmiedel, James Clarke, Patrick O’Rourke, Aruna D. de Silva, Eva Harris, Bjoern Peters, Gregory Seumois, Daniela Weiskopf, Alessandro Sette, Pandurangan Vijayanand. Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis. Science Immunology 

Catherine C. Bell, Anita C. A. Dankers, Volker M. Lauschke, Rowena Sison-Young, Roz Jenkins, Cliff Rowe, Chris Goldring, Kevin Park, Sophie Regan, Tracy Walker,  Chris Schofield, Audrey Baze, Alison J. Foster, Dominic Williams, Amy W. M. van de Ven, Frank Jacobs, Jos van Houdt3, Tuula Lähteenmäki, Jan Snoeys, Satu Juhila, Lysiane Richert, 
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Tania Carrillo-Roa, Christiana Labermaier, Peter Weber, David P. Herzog, Caleb Lareau, Sara Santarelli, Klaus V. Wagner, Monika Rex-Haffner, Daniela Harbich, Sebastian H. Scharf, Charles B. Nemeroff, Boadie W. Dunlop, W. Edward Craighead, Helen S. Mayberg, Mathias V. Schmidt, Manfred Uhr, Florian Holsboer, Inge Sillaber, Elisabeth . Binder, Marianne B. Müller. Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. PLOS

Niklas Landberg, Sofia von Palffy, Maria Askmyr, Henrik Lilljebjörn, Carl Sandén, Marianne Rissler, Satu Mustjoki, Henrik Hjorth-Hansen, Johan Richter, Helena Ågerstam, Marcus Järås, Thoas Fioretos. CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody based therapeutic targeting. Haematologica 

Gabriel Beikircher, Walter Pulverer, Manuela Hofner, Christa Noehammer, Andreas Weinhaeusel. Multiplexed and Sensitive DNA Methylation Testing Using Methylation-Sensitive Restriction Enzymes “MSRE-qPCR". DNA Methylation Protocols 

Kanaga Arul Nambi Rajan, Marwa Khater, Francesca Soncin, Donald Pizzo, Matteo Moretto-Zita, Jonathan Pham, Orysya Stus, Pooja Iyer, Veronique Tache, Louise C. Laurent, Mana M. Parast. Sirtuin1 is required for proper trophoblast differentiation and placental development in mice. Placenta Journal 

Paula Savola, Oscar Brück, Thomas Olson, Tiina Kelkka, Markku J. Kauppi, Panu E Kovanen, Soili Kytölä, Tuulikki Sokka-Isler, Thomas P. Loughran, Marjatta Leirisalo-Repo, Satu Mustjoki. Somatic STAT3 Mutations In The Felty Syndrome: An Implication For A Common Pathogenesis With Large Granular Lymphocyte Leukemia. Haematologica 

Linn S. Mamsen, Emil H. Ernst, Rehannah Borup, Agnete Larsen, Rasmus H. Olesen, Erik Ernst, Richard A. Anderson, Stine G. Kristensen, Claus Y. Andersen. Temporal expression pattern of genes during the period of sex differentiation in human embryonic gonads. Scientific Reports 

Hiba Sabra, Molly Brunner, Vinay Mandati, Bernhard Wehrle-Haller, Dominique Lallemand, Anne-Sophie Ribba, Genevieve Chevalier, Philippe Guardiola, Marc R. Block, and Daniel Bouvard. β1 integrin dependent Rac/group I PAK signaling mediates YAP activation of Yes associated protein 1 (YAP1) via NF2/merlin. Journal of Biological Chemistry 

Messner Simon, Fredriksson Lisa, Lauschke Volker M., Roessger Katrin, Escher Claudia, Bober Magdalena, Kelm Jens M., Ingelman-Sundberg Magnus, Moritz Wolfgang. Transcriptomic, Proteomic, and Functional Long-term Characterization of Multicellular Three-Dimensional Human Liver Microtissues. In Vitro Toxicology

Tomasz Ahrends, Aldo Spanjaard, Bas Pilzecker, Nikolina Bąbała, Astrid Bovens, Yanling Xiao, Heinz Jacobs, Jannie Borst. CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness. Immunity

Nathan L. Price, Noemi Rotllan, Alberto Canfrán-Duque, Xinbo Zhang, Paramita Pati, Noemi Arias, Jack Moen, David A. Ford, Ángel Baldán, Yajaira Suárez, Carlos Fernández-Hernando. Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis. Cell Reports 

Darragh Duffy, Vincent Rouilly, Cecile Braudeau, Véronique Corbière, Raouf Djebali, Marie-Noelle Ungeheuer, Regis Josien, Samuel T. LaBrie, Olivier Lantz, Delphine Louis, Eva Martinez-Caceres, Francoise Mascart, Jose G.Ruiz de Morales, Catherine Ottone, Lydia Redjah, Nina Salabert-Le Guen, Alain Savenay, Manfred Schmolz, Matthew L. Albert. Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study. Clinical Immunology 

 

Mia Eriksson, Pablo Peña-Martínez, Ramprasad Ramakrishnan, Marion Chapellier, Carl Högberg, Gabriella Glowacki, Christina Orsmark-Pietras, Talía Velasco-Hernández, Vladimir Lj Lazarević, Gunnar Juliusson, Jörg Cammenga, James C. Mulloy, Johan Richter, Thoas Fioretos, Benjamin L. Ebert and Marcus Järås. Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells. American society of Hematology 

Lindstedt, Malin, Borrebaeck, Carl A. K, Johansson, Henrik, Albrekt, Ann-sofie, Forreryd, Andrew. Analytical Methods and Arrays for Use in the Same. FPO

Tharini A. Selvakumar, Sudeep Bhushal, Ulrich Kalinke, Dagmar Wirth, Hansjörg Hauser, Mario Köster, Mathias W. Hornef. Identification of a Predominantly Interferon-λ-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells. Frontiers in immunology 

Yanling Xiao, Jara Palomero, Joanna Grabowska, Liqin Wang, Iris de Rink, Luuk van Helvert and Jannie Borst. Macrophages and osteoclasts stem from a bipotent progenitor downstream of a macrophage/osteoclast/dendritic cell progenitor. Blood advances

Kathrin S. Zallera, Henrik Johansson, Trine Østergaard Lund, Nanna N.Kristensen, Erwin L.Roggen, Malin Lindstedt. An alternative biomarker-based approach for the prediction of proteins known to sensitize the respiratory tract. Toxicology in Vitro 

 

 

Robin Mesnage, Alexia Phedonos, Matthew Arno, Sucharitha Balu, J. Christopher Corton, Michael N. Antoniou. Editor’s Highlight: Transcriptome Profiling Reveals Bisphenol A Alternatives Activate Estrogen Receptor Alpha in Human Breast Cancer Cells. Toxicological sciences

Svante Resjö, Maja Brus, Ashfaq Ali, Harold J. G. Meijer, Marianne Sandin, Francine Govers, Fredrik Levander, Laura Grenville-Briggs, Erik Andreasson. Proteomic analysis of Phytophthora infestans reveals the importance of cell wall proteins in pathogenicity. MCP

Berntssen, Sundal, Olsvik, Amlund, Rasinger, Sele, Hamre, Hillestad, Buttle, Ørnsrud. Sensitivity and toxic mode of action of dietary organic and inorganic selenium in Atlantic salmon (Salmo salar). Aquatic Toxicology 

Tobias Ottoa, Sheyla V. Candidoa, Mary S. Pilarza, Ewa Sicinskac, Roderick T. Bronsond, Michaela Bowdene, Iga A. Lachowicza, Kristin Mulrya, Anne Fassla, Richard C. Hana, Emmanuelle S. Jecroisa, and Piotr Sicinskia. Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. PNAS

Fikret Rifatbegovic, Christian Frech, M. Reza Abbasi, Sabine Taschner-Mandl, Tamara Weiss, Wolfgang M. Schmidt, Iris Schmidt, Ruth Ladenstein, Inge M. Ambros, Peter F. Ambros. Neuroblastoma cells undergo transcriptomic alterations upon dissemination into the bone marrow and subsequent tumor progression. 
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Rebecca Lawson, Wolfgang Maret, Christer Hogstrand. Expression of the ZIP/SLC39A transporters in β-cells: a systematic review and integration of multiple datasets. BioMed Central

Kshtij Arora, Munita Bal, Angela Shih, Andrea Moy, Lawerence Zukerberg, Ian Brown, Xiuli Liu, Paul Kelly, Esther Oliva, John Mullen, Soomin Ahn, Kyoung-Mee Kim, Vikram Deshpande. Fetal-type gastrointestinal adenocarcinoma: a morphologically distinct entity with unfavourable prognosis. Journal of clinical pathology

Lydie Morel, Ming Sum R. Chiang, Haruki Higashimori, Temitope Shoneye, Lakshmanan K Iyer, Julia Yelick, Albert Tai and Yongjie Yang. Molecular and Functional Properties of Regional Astrocytes in the Adult Brain. Journal of Neuroscience

Ikram Belghit, Josef D. Rasinger, Svenja Heesch, Irene Biancarosa, Nina Liland, Bente Torstensen, Rune Waagbø, Erik-Jan Lock, Christian G. Bruckner. In-depth metabolic profiling of marine macroalgae confirms strong biochemical differences between brown, red and green algae. Science direct

Kean-Chang Phang, Ariz Akhter, Nur Maya Sabrina Tizen, Faridah Abd Rahman, Raja Zahratul Azma, Ghaleb Elyamany, Meer-Taher Shabani-Rad, Noraidah Masir, Adnan Mansoor. Comparison of protein-based cell-of-origin classification to the Lymph2Cx RNA assay in a cohort of diffuse large B-cell lymphomas in Malaysia. Journal of clinical pathology

Abby K.Wegehaupt, Ellen K.Roufs, Cory R.Hewitt, Marisela L.Killian, Oxana Gorbatenko, Cynthia M.Anderson, M. Scott Killian. Recovery and assessment of leukocytes from LR Express filters. Science direct

Xian Wei Su, Gang Lu, Chi Kwan Leung, Qiang Liu, Yi Li, Kam Sze Tsang, Shi Dou Zhao, Danny Tat Ming Chan, Hsiang Fu Kung, Wai Sang Poon. miR-181d regulates human dendritic cell maturation through NF-κB pathway. Cell proliferation

Linda Magnusson, Nils Hansen, Karim H. Saba, Jenny Nilsson, Thoas Fioretos, Pehr Rissler, Karolin H. NordLoss of the tumor suppressor gene AIP mediates the browning of human brown fat tumors. The journal of pathology

Mesnage Robin, Phedonos Alexia, Biserni Martina, Arno Matthew, Balu Sucharitha J, Corton Christopher, Ugarte Ricardo, Antoniou Michael N. Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents. Science direct

Daniünaité Kristina. Diagnostic and prognostic DNA methylation biomarkers of prostate cancer.Vilnius University

Havjin Jacob, Luka Stanisavljevic, Kristian Eeg Storli, Olav Dahl, Mette Pernille Myklebust. Microrna signature as a potential biomarker for predicting survival in colon cancer. Cancer research

Rademacher Sebastian. Cytoskeletal dysregulation in the motoneuron disease Spinal Muscular Atrophy (SMA). University of Veterinary Medicine Hannover

Petter Skoog, Mattias Ohlsson, Mårten Ferno, Lisa Rydén, Carl A. K. Borrebaeck, Christer Wingren. Tumor tissue protein signatures reflect histological grade of breast cancer. Pro Quest

K Meldrum, TW Gant, MO Leonard. Diesel exhaust particulate associated chemicals attenuate expression of CXCL10 in human primary bronchial epithelial cells. Toxicology in Vitro

Berkley E. Gryder, Marielle E. Yohe, Hsien-Chao Chou, Xiaohu Zhang, Joana Marques, Marco Wachtel, Beat Schaefer, Nirmalya Sen, Young Song, Alberto Gualtieri, Silvia Pomella, Rossella Rota, Abigail Cleveland, Xinyu Wen, Sivasish Sindiri, Jun S. Wei, Frederic G. Barr, Sudipto as, Thorkell Andresson, Rajarshi Guha, Madhu Lal-Nag, Marc Ferrer, Jack F. Shern, Keji Zhao, Craig J. Thomas, Javed Khan. PAX3-FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability. Cancer Discovery

Hao Hu, Michael E. Wisniewski, Ahmed Abdelfattah, Xiaodong Zheng. Biocontrol activity of a cold-adapted yeast from Tibet against gray mold in cherry tomato and its action mechanism. Extremophiles

Carolyn D. Kramer, Alexandra M. Simas, Xianbao He, Robin R. Ingalls, Ellen O. Weinberg, Caroline Attardo Genco. Distinct roles for dietary lipids and Porphyromonas gingivalis infection on atherosclerosis progression and the gut microbiotaAnaerobe

Selena Ferrian, Claudia Manca, Sugnet Lubbe, Francesca Conradie, Nazir Ismail, Gilla Kaplan, Clive M. Gray , Dorothy Fallows. A combination of baseline plasma immune markers can predict therapeutic response in multidrug resistant tuberculosis. PLOS One

Sebastian Marwitz, Sofia Depner, Dmytro Dvornikov, Ruth Merkle, Magdalena Szczygiel, Karin Müller-Decker, Philippe Lucarelli, Marvin Wäsch, Heimo Mairbäurl, Klaus F. Rabe, Christian Kugler, Ekkehard Vollmer, Martin Reck, Swetlana Scheufele, Maren Kröger, Ole Ammerpohl, Reiner Siebert,
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C Unger, N Kramer, D Unterleuthner, M Scherzer, A Burian, A Rudisch, M Stadler, M Schlederer, D Lenhardt, A Riedl, S Walter, A Wernitznig, L Kenner, M Hengstschläger, J Schüler, W Sommergruber and H Dolznig. Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms. Oncogene

Rachel Waller, Emily F. Goodall, Marta Milo, Jonathan Cooper-Knock, Marc Da Costa, Esther Hobson, Mbombe Kazoka, Helen Wollff, Paul R. Heath, Pamela J. Shaw*, Janine Kirby. Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS). Neurobiology of Aging

KF Mose, M Burton, M Thomassen, F Andersen, T. A. Kruse, Q. Tan, L. Skov, M. A. Røpke, T. Litman,
O. Clemmensen, B. W. Kristensen, P. S. Friedmann, K. E. Andersen. The gene expression and immunohistochemical time-course of diphenylcyclopropenone induced contact allergy in healthy humans following repeated epicutaneous challenges. Experimental Dermatology

Vinko Palada. Molecular mechanisms of muscle pain associated with myotonic dystrophy type II. Dissertation, Freie University of Berlin

JD Rasinger, AK Lundebye, SJ Penglase, S Ellingsen. Methylmercury Induced Neurotoxicity and the Influence of Selenium in the Brains of Adult Zebrafish (Danio rerio). International Journal of Molecular Sciences

W Zhang, MM Morshed, K Noyan, A Russom. Quantitative humoral profiling of the HIV-1 proteome in elite controllers and patients with very long-term efficient antiretroviral therapy. Scientific Reports

Melanie Spitzwieser, Elisabeth Entfellner, Bettina Werner, Walter Pulverer, Georg Pfeiler, Stefan Hacker and Margit Cichna-Mark. Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients. BMC Cancer

Kathrin S. Zeller, Andy Forreryd,  Tim Lindberg, Robin Gradin, Aakash Chawade, Malin Lindstedt. The GARD platform for potency assessment of skin sensitizing chemicalsALTEX Online

Thoas Fioretos, Marcus Järås. Anti-IL1RAP Antibodies and Their Use for Treating HumanFPO

Maria Rossing, Christina Westmose Yde,  Astrid Sehested, Olga Østrup, David Scheie, Volodia Dangouloff-Ros, Birgit Geoerger, Gilles Vassal, Karsten Nysom. Genomic diagnostics leading to the identification of a TFG-ROS1 fusion in a child with possible atypical meningioma. Cancer Genetics

Isaac Engel, Grégory Seumois, Lukas Chavez, Daniela Samaniego-Castruita, Brandie White, Ashu Chawla, Dennis Mock, Pandurangan Vijayanand & Mitchell Kronenberg. Innate-like functions of natural killer T cell subsets result from highly divergent gene programs. Nature Immunology

Martin Nue Møller, Svend Kirkeby, Jonas Vikeså, Finn Cilius Nielsen, Per Cayé-Thomasen. The human endolymphatic sac expresses natriuretic peptides. Laryngoscope

Megha Rajasekhar, Anton M. Olsson, Kathryn J.A. Steel, Mirella Georgouli, Ushan Ranasinghe, Christine Brender Read. Klaus S. Frederiksen, Leonie S. Taams. MicroRNA-155 contributes to enhanced resistance to apoptosis in monocytes from patients with rheumatoid arthritis. Journal of Autoimmunity

Afnan Ali Al Sultan. The effects of TAR DNA binding protein mutations on RNA processing associated with
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James E. Scriven, Lisa M. Graham, Charlotte Schutz, Thomas J. Scriba, Katalin A. Wilkinson, Robert J. Wilkinson, David R. Boulware, Britta C. Urban, David G. Lalloo,  Graeme Meintjes. A glucuronoxylomannan-associated immune signature, characterized by monocyte deactivation and raised IL-10, is a predictor of death in cryptococcal meningitis. Journal of Infectious Diseases Advance Access

Catherine C Bell, Volker M Lauschke, Sabine U Vorrink, Henrik Palmgren, Roger Duffin, Tommy B Andersson and Magnus Ingelman-Sundberg. Transcriptional, functional and mechanistic comparisons of stem cell-derived hepatocytes, HepaRG cells and 3D human hepatocyte spheroids as predictive in vitro systems for drug-induced liver injury. Drug Metabolism and Disposition

Paul J. Planet, Dane Parker,Taylor S. Cohen, Hannah Smith, Justinne D. Leon, Chanelle Ryan, Tobin J. Hammer,Noah Fierer, Emily I. Chen,Alice S. Prince. Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection. mBio

A Schridde, C C Bain,  J U Mayer, J Montgomery, E Pollet, , B Denecke, S W F Milling, S J Jenkins, M Dalod, S Henri, B Malissen, O Pabst and A Mcl Mowat. Tissue-specific differentiation of colonic macrophages requires TGFß receptor-mediated signaling. Mucosal Immunology

Sung Yun Jung, Jong Min Choi, Maxime W.C. Rousseaux, Anna Malovannaya, Jean J Kim, Joachim Kutzera, Yi Wang, Yin Huang, Weimin Zhu, Suman Maity, Huda Yahya Zoghbi and Jun Qin. An anatomically resolved mouse brain proteome reveals Parkinson disease-relevant pathways. Molecular and Cellular Proteomics

Sumadi Lukman Anwar, Ulrich Lehmann. DNA methylation and expression of Homeobox gene family as diagnostic and prognostic markers in human hepatocellular carcinoma. Journal of the medical sciences

Sumadi Lukman Anwar, Till Krech, Britta Hasemeier, Elisa Schipper, Nora Schweitzer, Arndt Vogel, Hans Kreipe, Reena Buurman, Britta Skawran, Ulrich Lehmann. hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma. World Journal of Gastroenterology

Aminatou Kone, Antoine Dara, Amadou Niangaly, Indranil Sinha, David Brodin, Bakary Fofana, Souleymane Dama, Demba Dembele, Bakary Sidibe, Nouhoum Diallo, Mahamadou Thera, Issaka Sagara, Karin Wright, Anders Björkman, Jose Gil, Ogobara Doumbo, Abdoulaye Djimde. Effect of artesunate monotherapy on plasmodium falciparum in vivo genomics expression. BMJ Global Health

Qinghua Cao, Fang Liu, Kaiyuan Ji, Ni Liu, Yuan He, Wenhui Zhang and Liantang Wang. MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression. Journal of Experimental & Clinical Cancer Research

Dania Zhivaki, Sébastien Lemoine, Annick Lim, Ahsen Morva, Pierre-Olivier Vidalain, Liliane Schandene, Nicoletta Casartelli, Marie-Anne Rameix-Welti, Pierre-Louis Hervé, Edith Dériaud, Benoit Beitz, Maryline Ripaux-Lefevre, Jordi Miatello, Brigitte Lemercier, Valerie Lorin, Delphyne Descamps, Jenna Fix, Jean-François Eléouët, Sabine Riffault, Olivier Schwartz, Fabrice Porcheray, Françoise Mascart, Hugo Mouquet, Xiaoming Zhang, Pierre Tissières, Richard Lo-Man. Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity. Immunity

K. Hoff, A. Kahlert, E. Audain, H. Milting, R. Siebert, H.-H. Kramer, O. Ammerpohl, M.-P. Hitz. Differential DNA-Methylation Pattern in Cardiac Tissue Samples from Patients with Congenital Heart Disease. The Thoracic and Cardiovascular Surgeon

Souren Mkrtchian,  Kian Leong Lee, Jessica Kåhlin, Anette Ebberyd, Lorenz Poellinger, Malin Jonsson Fagerlund,  Lars I. Eriksson, Hypoxia regulates microRNA expression in the human carotid bodyExperimental Cell Research

Robert F. Stanley, Richard T. Piszczatowski, Boris Bartholdy, Kelly Mitchell, Wendy M. McKimpson, Swathi Narayanagari, Dagmar Walter, Tihomira I. Todorova, Cassandra Hirsch, Hideki Makishima, Britta Will, Christine McMahon, Kira Gritsman, Jaroslaw P. Maciejewski, Richard N. Kitsis, Ulrich Steidl. A myeloid tumor suppressor role for NOL3JEM, The Journal of Experimental Medicine

R Mesnage, M Arno, GE Séralini, MN Antoniou. Transcriptome and metabolome analysis of liver and kidneys of rats chronically fed NK603 Roundup-tolerant genetically modified maize. Environmental Sciences Europe

Anna K. Wakeland, Francesca Soncin, Matteo Moretto-Zita, Ching-Wen Chang, Mariko Horii, Don Pizzo, Katharine K. Nelson, Louise C. Laurent, Mana M. Parast'Correspondence information about the author Mana M. Parast. Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor–Dependent Manner. The American Journal of Pathology

Marcin Golec, Matthias Wielscher, Marta Kinga Lemieszek, Klemens Vierlinger, Czeslawa Skórska, Sophia Huetter, Jolanta Sitkowska, Barbara Mackiewicz, Anna Góra-Florek, Rolf Ziesche, Hagai Yanai, Vadim E. Fraifeld, Janusz Milanowski,Jacek Dutkiewicz. Middle age enhances expression of innate immunity genes in a female mouse model of pulmonary fibrosis. Biogerontology

Høj Thomsen L. Fog-Tonnesen M, Nielsen Fink L. Norlin J, de Vinuesa A.G, Krarup Hansen T, de Heer E, ten Dijke P, Rosendahl A. Smad2 Phosphorylation in Diabetic Kidney Tubule Epithelial Cells Is Associated with Modulation of Several Transforming Growth Factor-ß Family Members. Nephron

K. Dale, J.D. Rasinger, K.L. Thorstensen, S. Penglase, S. Ellingsen. Vitamin E reduces endosulfan-induced toxic effects on morphology and behavior in early development of zebrafish (Danio rerio). Food and Chemical Toxicology

Cancan Peng Wenli Ma Wei Xia Wenling Zheng. Integrated analysis of differentially expressed genes and pathways in triple-negative breast cancer. Molecular Medicine Reports

Deborah A. Weighill, Daniel Jacobson. Network Metamodeling: Effect of Correlation Metric Choice on Phylogenomic and Transcriptomic Network Topology. Advances in Biochemical Engineering/Biotechnology

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Igor Stzepourginski, Giulia Nigro, Jean-Marie Jacob, Sophie Dulauroy, Philippe J. Sansonetti, Gérard Eberl and Lucie Peduto. CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury. PNAS

Julia Hengst, Christine Susanne Falk,  Verena Schlaphoff, Katja Deterding, Michael Peter Manns, Markus Cornberg, Heiner Wedemeyer. Direct-Acting Antiviral–Induced Hepatitis C Virus Clearance Does Not Completely Restore the Altered Cytokine and Chemokine Milieu in Patients With Chronic Hepatitis CThe Journal of Infectious Diseases

Henning Kempf, , Ruth Olmer, , Alexandra Haase, , Annika Franke, , Emiliano Bolesani, , Kristin Schwanke, , Diana Robles-Diaz, Michelle Coffee, Gudrun Göhring, Gerald Dräger, Oliver Pötz, Thomas Joos, Erik Martinez-Hackert, Axel Haverich, Falk F. R. Buettner, Ulrich Martin, Robert Zweigerdt. Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells. Nature Communications

Mariacarla Andreozzi,  Cristina Quintavalle, David Benz, Luca Quagliata, Matthias Matter, Diego Calabrese, Nadia Tosti, Christian Ruiz, Francesca Trapani, Luigi Tornillo, Alfredo Fusco, §, Markus H Heim, Charlotte KY Ng, Pierlorenzo Pallante, Luigi M Terracciano, Salvatore Piscuoglio. HMGA1 Expression in Human Hepatocellular Carcinoma Correlates with Poor Prognosis and Promotes Tumor Growth and Migration in in vitro Models. Neoplasia

Anja Ziegler, Helen Everett, Eman Hamza, Mattia Garbani, Vinzenz Gerber, Eliane Marti and Falko Steinbach. Equine dendritic cells generated with horse serum have enhanced functionality in comparison to dendritic cells generated with fetal bovine serum. BMC Veterinary Research

Mr Luke Jennings, Dr. Helen Elizabeth Colley, Dr. Jane Ong, Dr. Foti Panagakos, Dr. James Masters, Dr. Harsh Trivedi, Dr. Craig Murdoch, and Dr. Simon Whawell. Development and characterisation of in vitro human oral mucosal equivalents derived from immortalised oral keratinocytes. Tissue Engineering Part C: Methods

Franck Limonier, Katleen Van Steendam, Geneviève Waeterloos, Koen Brusselmans, Myriam Sneyers, Dieter Deforce. An application of mass spectrometry for quality control of biologicals: highly sensitive profiling of plasma residuals in human plasma-derived immunoglobulin. Journal of Proteomics

Michael J. A. Williams, L. Vicky Phillips, Ivor F. Galvin, Richard W. Bunton, Gregory T. Jones. Integrated microRNA and messenger RNA analysis in aortic stenosis. Scientific Reports

Sadhvi Nithiananthan, Aileen Crawford, Johnathan Cooper Knock, Daniel W. Lambert,
Simon A. Whawell. Physiological Fluid Flow Moderates Fibroblast Responses to TGF-ß1. Journal of Cellular Biochemistry

Danielle Ahn,  Hernán Peñaloza, Zheng Wang, Matthew Wickersham, Dane Parker, Purvi Patel, Antonius Koller, Emily I. Chen, Susan M. Bueno, Anne-Catrin Uhlemann, and Alice Prince. Acquired resistance to innate immune clearance promotes Klebsiella pneumoniae ST258 pulmonary infection. JCI insight

Stephen J. Walker, Daniel P. Beavers, John Fortunato & Arthur Krigsman. A Putative Blood-Based Biomarker for Autism Spectrum Disorder-Associated Ileocolitis. Scientific Reports

Pål A. Olsvik, , Marc H.G. Berntssen, Liv Søfteland. In vitro toxicity of pirimiphos-methyl in Atlantic salmon hepatocytes. Toxicology in Vitro

Tiziano Donnarumma, George R. Young,  Julia Merkenschlager, Urszula Eksmond, Nadine Bongard, Stephen L. Nutt, Claude Boyer, Ulf Dittmer, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Wibke Bayer, George Kassiotis. Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus. Cell Reports

J. Keith Killian, Lambert C.J. Dorssers, Britton Trabert, Ad J.M. Gillis, Michael B. Cook, Yonghong Wang, Joshua J. Waterfall, Holly Stevenson, William I. Smith Jr., Natalia Noyes, Parvathy Retnakumar, J. Hans Stoop, J. Wolter Oosterhuis, Paul S. Meltzer, Katherine A. McGlynn and Leendert H.J. Looijenga. Imprints and DPPA3 are bypassed during pluripotencyand differentiation-coupled methylation reprogramming in testicular germ cell tumors. Genome Research

Michael H. Limberg, Julia Schulte, Tita Aryani, Regina Mahr, Meike Baumgart, Michael Bott, Wolfgang Wiechert, Marco Oldiges. Metabolic profile of 1,5-diaminopentane producing Corynebacterium glutamicum under scale-down conditions: Blueprint for robustness to bioreactor inhomogeneities. Biotechnology and Bioengineering

Samaneh Masoumi, Aditya Harisankar,  Aileen Gracias, Fabian Bachinger, Temesgen Fufa, Gayathri Chandrasekar, Frank Gaunitz, Julian Walfridsson, and Satish S Kitambi. Understanding cytoskeleton regulators in glioblastoma multiforme for therapy design. Drug Design, Development and Therapy

P Delfani, G Sturfelt, B Gullstrand, A Carlsson, M Kassandra, C A K Borrebaeck, A A Bengtsson, and C Wingren. Deciphering systemic lupus erythematosus-associated serum biomarkers reflecting apoptosis and disease activity. Lupus

J. Hengst, Falk, V. Schlaphoff, K. Deterding, M.P. Manns, M. Cornbergand H. Wedemeyer. DAA-induced HCV clearance does not completely restore the altered cytokine and chemokine milieu in patients with chronic hepatitis C. The Journal of Infectious Diseases

Marie Szymanowski,  Maria Salomon Estebanez, Raja Padidela, Bing Han, Karolina Mosinska, Adam Stevens, Lena Damaj, Florence Pihan-Le Bars, Emilie Lascouts, Rachel Reynaud, Catherine Ferreira, Claire Bansept, Pascale de Lonlay,  Cécile Saint-Martin, Mark J. Dunne, Indraneel Banerjee, Jean-Baptiste Arnoux. mTOR inhibitors for the treatment of severe congenital hyperinsulinism: perspectives on limited therapeutic success. The Journal of Endoctrinology & Metabolism

Melanie R. Hassler, Walter Pulverer, Ranjani Lakshminarasimhan, Andreas Weinhaeusel, Suzanne D. Turner, Gerda Egger. Insights into the Pathogenesis of Anaplastic LargeCell Lymphoma through Genome-wide DNA Methylation Profiling. Cell Reports

Annette Bernhard, Marc H.G. Berntssen, , Anne-Katrine Lundebye, , Anita Røyneberg Alvheim, Lene Secher Myrmel, , Even Fjære, , Bente E. Torstensen, Karsten Kristiansen, , Lise Madsen, Trond Brattelid, Josef D. Rasinger. Marine fatty acids aggravate hepatotoxicity of a-HBCD in juvenile female BALB/c mice. Food and Chemical Toxicolog

Hristo Georgiev, Inga Ravens, Charaf Benarafa, Reinhold Förster & Günter Bernhardt. Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets. Nature Communications

Michael K. Skinner. Ovary Systems Biology. Lecture at Washington State university

Sebastian Marwitz, Sofia Depner, Dmytro Dvornikov, Ruth Merkle, Magdalena Szczygiel, Karin Müller-Decker, Philippe Lucarelli, Marvin Wäsch, Heimo Mairbäurl, Klaus F. Rabe, Christian Kugler, Ekkehard Vollmer, Martin Reck, Swetlana Scheufele, Maren Kröger, Ole Ammerpohl, Reiner Siebert, Torsten Goldmann, Ursula Klingmüller. Downregulation of the TGF-ß pseudoreceptor BAMBI in non-small cell lung cancer enhances TGF-ß signaling and invasion. Cancer Research AACR

Ann-Cathrine Larsen; Lauge H. Mikkelsen; Rehannah Borup; Katalin Kiss; Peter B. Toft; Christian von Buchwald; Sarah E. Coupland; Jan U. Prause; Steffen Heegaard. MicroRNA Expression Profile in Conjunctival Melanoma

Zeng MN, Ma WL, Zheng W. Bioinformatics analysis of microRNA comprehensive regulatory network in B- cell acute lymphoblastic leukemia. NCBI PubMed

Volker M. Lauschke, Sabine U. Vorrink, Sabrina M. Moro, Fatemah Reyazee, Åsa Nordling, Delilah F. Hendriks, Catherine C. Bell, Rowena Sison-Young, B. Kevin Park, 
Christopher E. Goldring, Ewa Ellis, Inger Johansson, Souren Mkrtchian, Tommy B. Andersson, Magnus Ingelman-Sundberg. Massive rearrangements of cellular miRNA signatures are key drivers of hepatocyte dedifferentiation. Hepatology

Elena Matsa, Paul W. Burridge, Kun-Hsing Yu,  John H. Ahrens1, Vittavat Termglinchan, Haodi Wu, Chun Liu, Praveen Shukla, Nazish Sayed, Jared M. Churko, Ningyi Shao, Nicole A. Woo, Alexander S. Chao, Joseph D. Gold1, Ioannis Karakikes,  Michael P. Snyder, Joseph C. Wu. Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro. Cell Stem Cell

Alejandra Urrutia,  Darragh Duffy, Vincent Rouilly, Céline Posseme, Raouf Djebali, Gabriel Illanes, Valentina Libri, Benoit Albaud, David Gentien, Barbara Piasecka, Milena Hasan, Magnus Fontes,  Lluis Quintana-Murci, Matthew L. Albert. Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses. Cell Reports

Bruno Stuhlmüller, Karsten Mans, Neeraj Tandon, Marc O. Bonin, Biljana Smiljanovic, Till A. Sörensen, Pascal Schendel, Peter Martus, Joachim Listing, Jacqueline Detert, Marina Backhaus, Thomas Neumann, Robert J. Winchester, Gerd-R. Burmester, Thomas Häupl. Genomic stratification by expression of HLA-DRB4 alleles identifies differential innate and adaptive immune transcriptional patterns - A strategy to detect predictors of methotrexate response in early rheumatoid arthritis. Clincal Immunology

W Dunn, A Burgun, MO Krebs, B Rance. Exploring and visualizing multidimensional data in translational research platforms. Briefings in Bioinformatics

Fang Liu, Yuan He, Qinghua Cao, Ni Liu, and Wenhui Zhang. TBL1XR1 Is Highly Expressed in Gastric Cancer and Predicts Poor Prognosis. Disease Markers

Dongfeng Chen, Junxiong Zheng, Natalija Gerasimcik, Kristina Lagerstedt, Helene Sjögren, Jonas Abrahamsson, Linda Fogelstrand, Inga-Lill Mårtensson. The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia. PLOSOne

Olga Bogatyrova. Mutations in regulators of the epigenome and their effects on the DNA methylome.  Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg

A Forreryd, KS Zeller, T Lindberg, H Johansson, M Lindstedt. From genome-wide arrays to tailor-made biomarker readout – Progress towards routine analysis of skin sensitizing chemicals with GARD. Toxicology in Vitro

Ariz Akhter, Muhammad Kashif Mughal, Ghaleb Elyamany, Gary Sinclair, Raja Zahratul Azma, Noraidah Masir, Salwati Shuib, Fariborz Rashid-Kolvear, Meer-Taher Shabani-Rad, Douglas Allan Stewart and Adnan Mansoor. Diagnostic Pathology

Bjørn Henrik Hansen, Kai K. Lie, Trond R. Størseth, Trond Nordtug, Dag Altin & Pål A. Olsvik. Exposure of first-feeding cod larvae to dispersed crude oil results in similar transcriptional and metabolic responses as food deprivation. Journal of Toxicology and Environmental Health

J Carlos Villaescusa, Bingsi Li, Enrique M Toledo, Pia Rivetti di Val Cervo, Shanzheng Yang, Simon RW Stott, Karol Kaiser, Saiful Islam, Daniel Gyllborg, Rocio Laguna-Goya, Michael Landreh, Peter Lönnerberg, Anna Falk, Tomas Bergman, Roger A Barker, Sten Linnarsson, Licia Selleri, View ORCID ProfileErnest Arenas. A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease. The Embo Journal

Rowena L. Sison-Young, Volker M. Lauschke, Esther Johann, Eliane Alexandre, Sébastien Antherieu, Hélène Aerts, Helga H. J. Gerets, Gilles Labbe, Delphine Hoët, Martina Dorau, Christopher A. Schofield, Cerys A. Lovatt, Julie C. Holder, Simone H. Stahl, Lysiane Richert, Neil R. Kitteringham, Robert P. Jones, Mohamed Elmasry, Richard J. Weaver, Philip G. Hewitt, Magnus Ingelman-Sundberg, Chris E. Goldring, B. Kevin Park. A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity. Archives of Toxicology

Abrahan Hernández-Hernández, Ingrid Lilienthal, Nanaho Fukuda, Niels Galjart, and Christer Höög. CTCF contributes in a critical way to spermatogenesis and male fertility. Scientific Reports

Sine V. Winther, Tomi Tuomainen, Rehannah Borup, Pasi Tavi, Gudrun Antoons, and Morten B. Thomsen. Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling. Scientific Reports

Sofia Waldemarson, Emila Kurbasic, Morten Krogh, Paolo Cifani, Tord Berggård, Åke Borg and Peter James. Proteomic analysis of breast tumors confirms the mRNA intrinsic molecular subtypes using different classifiers: a large-scale analysis of fresh frozen tissue samples. Breast Cancer Research

Mohammed Ashrafi MB, ChB, Anil Sebastian PhD, Barbara Shih PhD, Nicholas Greaves PhD, Teresa Alonso-Rasgado PhD, Mohamed Baguneid MD, Ardeshir Bayat MB, BS, PhD. Whole genome microarray data of chronic wound debridement prior to application of dermal skin substitutes. Wound Repair and Regeneration

Christopher James Collins, Yawo A. Mondjinou, Bradley P. Loren, Sandra Torregrosa-Allen, Christopher J Simmons, Bennett D. Elzey, Nadia Ayat, Zheng-Rong Lu, and David H Thompson. Influence of Molecular Structure on the In Vivo Performance of Flexible Rod Polyrotaxanes. Biomacromolecules

Payam Delfani, Linda Dexlin Mellby, Malin Nordström, Andreas Holmér, Mattias Ohlsson, Carl A. K. Borrebaeck, Christer Wingren. Technical Advances of the Recombinant Antibody Microarray Technology Platform for Clinical Immunoproteomics. PLOS One

Francesco Nicoli, Email author, Mkunde Chachage†, Petra Clowes, Asli Bauer, Dickens Kowour, Barbara Ensoli, Aurelio Cafaro, Leonard Maboko, Michael Hoelscher, Riccardo Gavioli, Elmar Saathoff and Christof Geldmacher. Association between different anti-Tat antibody isotypes and HIV disease progression: data from an African cohort. BMC Infectious Diseases

Kevin A. Link, Shan Lin, Mahesh Shresth, Melissa Bowman, Mark Wunderlich, Clara D. Bloomfield, Gang Huang,c, and James C. Mulloy. Supraphysiologic levels of the AML1-ETO isoform AE9a are essential for transformation. PNAS

H. Sun, P. Liu, L. K. Nolan and S. J. Lamont. Thymus transcriptome reveals novel pathways in response to avian pathogenic Escherichia coli infection. Poultry Science Oxford Journals

WC Plaisted, A Zavala, E Hingco, H Tran, R Coleman, Thomas E. Lane, Jeanne F. Loring, Craig M. Walsh. Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis, PLOS One 

M Pudenz. Impact of soy isoflavones on DNA methylation in rat mammary glands-Dose-response aspects, critical time windows, and influence on carcinogenesis. Dissertation submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg

Zineb Mounir, Joshua M Korn, Thomas Westerling, Fallon Lin, Christina A Kirby, Markus Schirle, Gregg McAllister, Greg Hoffman, Nadire Ramadan, Anke Hartung, Yan Feng,  David Randal Kipp, Christopher Quinn, Michelle Fodor, Jason Baird, Marie Schoumacher, Ronald Meyer, James Deeds, Gilles Buchwalter, Travis Stams, Nicholas Keen, William R Sellers, Myles Brown, Raymond A Pagliarini. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor. eLife

Ann-Cathrine Larsen.  Conjunctival malignant melanoma in Denmark: epidemiology, treatment and prognosis with special emphasis on tumorigenesis and genetic profile. Acta Ophthalmologica

Julia Kolarova, Susanne Bens, Ole Ammerpohl, Alina C. Hilger, Rong Zhang, Heiko Reutter, Reiner Siebert. PLAGL1 epimutation and bladder exstrophy: Coincidence or concurrent etiology?  Birth Defects Research Part A: Clinical and Molecular Teratology

Vicente Martinez-Redondo, Paulo R. Jannig, Jorge C Correia1, Duarte M.S. Ferreira, Igor Cervenka, Jessica M. Lindvall, Indranil Sinha, Manizheh Izadi, Amanda T. Pettersson-Klein1, Leandro Z. Agudelo, Alfredo Gimenez-Cassina1, Patricia C. Brum, Karin Dahlman-Wright1 and Jorge L. Ruas3. Peroxisome proliferator-activated receptor gamma coactivator-1alpha isoforms selectively regulate multiple splicing events on target genes. The Journal of Biological Chemistry

Oluwajoba O. Akinjo,a Timothy W. Gant and Emma L. Marczylo.  Perturbation of epigenetic processes by doxorubicin in the mouse testis. Toxicology Research

Henrik Lilljebjörn, Rasmus Henningsson, Axel Hyrenius-Wittsten, Linda Olsson, Christina Orsmark-Pietras, Sofia von Palffy, Maria Askmyr, Marianne Rissler, Martin Schrappe, Gunnar Cario, Anders Castor, Cornelis J. H. Pronk, Mikael Behrendtz, Felix Mitelman, Bertil Johansson, Kajsa Paulsson, Anna K. Andersson, Magnus Fontes & Thoas Fioretos. Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia. Nature Communications 7

Aline Dupont , Felix Sommer, Kaiyi Zhang, Urska Repnik, Marijana Basic, André Bleich, Mark Kühnel, Fredrik Bäckhed, Yael Litvak, Marcus Fulde, Ilan Rosenshine, Mathias W. Hornef. Age-Dependent Susceptibility to Enteropathogenic Escherichia coli (EPEC) Infection in Mice. PLOS Pathogens

Catherine C. Bell, Delilah F. G. Hendriks,  Sabrina M. L. Moro, Ewa Ellis,  Joanne Walsh, Anna Renblom, ,Lisa Fredriksson Puigvert,  Anita C. A. Dankers, Frank Jacobs, Jan Snoeys, Rowena L, Sison-Young, Rosalind E. Jenkins, Åsa Nordling, Souren Mkrtchian, B. Kevin Park, Neil R. Kitteringham, Christopher E. P. Goldring, Volker M. Lauschke, Magnus Ingelman-Sundberg. Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease. Scientific Reports, Nature

T Weiss, S Taschner-Mandl, H Dodig , F Rifatbegovic, C Frech, IM Ambros, PF Ambros. Schwann cells secrete factors that impair neuroblastoma growth. Klinische Pädiatrie, (Clinical Research and Practice in Pediatrics)

Gitte L. Christensen, Maria L. B. Jacobsen, Anna Wendt, Ines G. Mollet, Josefine Friberg, Klaus S. Frederiksen, Michael Meyer, Christine Bruun, Lena Eliasson. Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents. Diabetologia

Gregory T. Jones, PhD; L. Victoria Phillips; Michael J.A. Williams, MBChB; Andre M. van Rij, MBChB; Tasnuva D. Kabir, MBChB, PhD. Two C-C Family Chemokines, Eotaxin and RANTES, Are Novel Independent Plasma Biomarkers for Abdominal Aortic Aneurysm. The Journal of the American Heart Association

Tiphaine Parrot, Mathilde Allard, Romain Oger, Houssem Benlalam, Diane Raingeard de la Blétière, Anne Coutolleau, Laurence Preisser, Juliette Desfrançois, Amir Khammari, Brigitte Dréno, Nathalie Labarrière, Yves Delneste, Philippe Guardiola and Nadine Gervois. IL-9 promotes the survival and function of human melanoma-infiltrating CD4+CD8+ double-positive T cells. European Journal of Immunology

Ignacio Sancho-Martinez, Emmanuel Nivet, Yun Xia, Tomoaki Hishida, Aitor Aguirre, Alejandro Ocampo, Li Ma, Robert Morey, Marie N. Krause, Andreas Zembrzycki, Olaf Ansorge, Eric Vazquez-Ferrer, Ilir Dubova, Pradeep Reddy, David Lam, Yuriko Hishida, Min-Zu Wu, Concepcion Rodriguez Esteban, Dennis O’Leary, Geoffrey M. Wahl. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Nature Communications

Somsundar Veppil Muralidharan. TARGETING MYC-DRIVEN TUMOURS BETing on ATR. Department of Surgery Institute of Clinical Sciences Sahlgrenska Academy at University of Gothenburg - Theses

Hristo Georgiev,  Inga Ravens, Charaf Benarafa, Reinhold Förster, Günter Bernhardt. Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets. Nature Communications 

Willem J. du Plessis, Léanie Kleynhans, Nelita du Plessis, Kim Stanley, Stephanus T. Malherbe, Elizna Maasdorp, Katharina Ronacher, Novel N. Chegou, Gerhard Walzl, Andre G. Loxton. The Functional Response of B Cells to Antigenic Stimulation: A Preliminary Report of Latent Tuberculosis. PLOS One

N. E. U. Hermansen, R. Borup, M. K. Andersen, A. J. Vangsted2, N. T. Clausen, D. L. Kristensen, F. C. Nielsen and P. Gimsing. Gene expression risk signatures maintain prognostic power in multiple myeloma despite microarray probe set translation. International Journal of Laboratory Hematology 

Ai Ing Lim, Silvia Menegatti,  Jacinta Bustamante, Lionel Le Bourhis, Matthieu Allez,  Lars Rogge, Jean-Laurent Casanova, Hans Yssel, and James P. Di Santo. IL-12 drives functional plasticity of human group 2 innate lymphoid cells. The Journal of Experimental Medicine

Rabih Moshouraba,  Vinko Paladac, Stefanie Grunwaldc, Ulrike Griebenc, Gary R. Lewina, Simone Spulerc. A Molecular Signature of Myalgia in Myotonic Dystrophy 2EBioMedicine

Wafa Kammoun-Rebai, Ikbel Naouar, Valentina Libri, Matthew Albert, Hechmi Louzir, Amel Meddeb-Garnaoui and Darragh Duffy. Protein biomarkers discriminate Leishmania major-infected and non-infected individuals in areas endemic for cutaneous leishmaniasis. BMC Infectious Diseases

Marc H.G. Berntssena, Robin Ørnsruda, Josef Rasingera, Liv Søftelanda, Erik-Jan Locka, Kjersti Kolåsa, Mari Morenb, Ketil Hyllande, Joana Silvac, Johan Johansend, Kai Liea. Dietary vitamin A supplementation ameliorates the effects of poly-aromatic hydrocarbons in Atlantic salmon (Salmo salar). Aquatic Toxicology

Pablo Carbonell-Bejerano , Virginia Rodríguez, Silvia Hernáiz, Carolina Royo, Silvia Dal Santo, Mario Pezzotti, José Miguel Martínez-Zapater. Reducing sampling bias in molecular studies of grapevine fruit ripening: transcriptomic assessment of the density sorting method. Theoretical and Experimental Plant Physiology

Wen Cheng, Chuanbao Zhang, Xiufang Ren, Yang Jiang, Sheng Han, Yang Liu, Jinquan Cai, Mingyang Li, Kuanyu Wang, Yanwei Liu, Huimin Hu, Qingbin Li, Pei Yang, Zhaoshi Bao, Anhua Wu. Bioinformatic analyses reveal a distinct Notch activation induced by STAT3 phosphorylation in the mesenchymal subtype of glioblastoma. Journal of Neurosurgery

József Prechl , Krisztián Papp, Zoltán Hérincs, Hajna Péterfy, Veronika Lóránd, Zoltán Szittner, Andone Estonba, Paolo Rovero, Ilaria Paolini, Jokin del Amo, Maria Uribarri, Maria Claudia Alcaro, Otsanda Ruiz-Larrañaga, Paola Migliorini, László Czirják. Serological and Genetic Evidence for Altered Complement System Functionality in Systemic Lupus Erythematosus: Findings of the GAPAID Consortium. PLOS One

Anna Afasizheva, Alexus Devine, Heather Tillman, King Leung Fung, Wilfred D. Vieira, Benjamin H. Blehm, Yorihisa Kotobuki, Ben Busby, Emily I. Chen and Kandice Tanner. Mitogen-activated protein kinase signaling causes malignant melanoma cells to differentially alter extracellular matrix biosynthesis to promote cell survival. BMC Cancer

Bilgin Candar-Cakir, Ercan Arican, Baohong Zhang. Small RNA and degradome deep sequencing reveals drought-and tissue-specific micrornas and their important roles in drought-sensitive and drought-tolerant tomato genotypes. Plant Biotechnology Journal

Kirsty Meldrum, Timothy W. Gant, Sameirah Macchiaruloa and Martin O. Leonard. Bronchial epithelial innate and adaptive immunity signals are induced by polycyclic aromatic hydrocarbons. Toxicology Research

R Vangoitsenhoven, H Wolden-Kirk, K Lemaire...Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in miceEffect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice. The Journal of Steroid Biochemistry and Molecular Biology,

Shankar Thangamani,  Haroon Mohammad, , Mostafa F. N. Abushahba,Tiago J. P. Sobreira, Victoria E. Hedrick,  Lake N. Pau & Mohamed N. Seleem. Antibacterial activity and mechanism of action of auranofin against multi-drug resistant bacterial pathogens. Scientific Reports

Lisa M Nilsson, Lydia C. Green, Somsundar Veppil Muralidharan, Dagsu Demir, Martin Welin, Joydeep Bhadury, Derek Logan, Björn Walse, and Jonas A. Nilsson. Cancer differentiation agent hexamethylene bisacetamide was likely the first BET bromodomain inhibitor in clinical trials, Cancer Research 

Pål A. Olsvika, Liv Søftelanda, Ernst M. Hevrøya, Josef D. Rasingera, Rune Waagbøa. Fish pre-acclimation temperature only modestly affects cadmium toxicity in Atlantic salmon hepatocytes. Journal of Thermal Biology

Oliver Popp, Dirk Müller, Katharina Didzus, Wolfgang Paul, Florian Lipsmeier,  Florian Kirchner, Jens Niklas, Klaus Mauch, Nicola Beaucamp. A hybrid approach identifies metabolic signatures of high-producers for Chinese hamster ovary clone selection and process optimization. Biotechnology and Bioengineering

Catherine Leclerc, Jacques Haeich, Francisco Aulestia, Marie-Claude
Kilhoffer, Andrew L. Miller, Isabelle N´eant, Sarah E. Webb, Etienne Schaeffer,
Marie-Pierre Junier, Herv´e Chneiweiss, Marc Moreau. Calcium signaling orchestrates glioblastoma development: Facts and conjunctures. BBA - Molecular Cell Research

J Davidsson, B Johansson. Methylation and expression analyses of Pallister-Killian syndrome reveal partial dosage compensation of tetrasomy 12p and hypomethylation of gene-poor regions on 12p. Epigenetics

Matthew Timothy Tierney, Anastasia Gromova, Francesca Boscolo Sesillo,  David Sala, Caroline Spenlé,  Gertraud Orend,  Alessandra Sacco. Autonomous Extracellular Matrix Remodeling Controls a Progressive Adaptation in Muscle Stem Cell Regenerative Capacity during Development. Cell Reports

Sasha A. Singh, Allison B. Andraski, Brett Pieper, Wilson Goh , Carlos O. Mendivil, 
Frank M. Sacks, Masanori Aikawa. Multiple apolipoprotein kinetics measured in human
HDL by high-resolution/accurate mass parallel reaction monitoring. Journal of Lipid Research

V Kuci, L Nordström, P Conrotto, S Ek. SOX11 and HIG-2 are cross-regulated and affect growth in mantle cell lymphoma.  Leukemia & Lymphoma

Matthias S. Matter, Jens U. Marquardt, Jesper B. Andersen, Cristina Quintavalle, 
Nikolay Korokhov, Jim K. Stauffer, Kosuke Kaji, Thomas Decaens, Luca Quagliata, Fathi Elloumi, Tanya Hoang, Alfredo Molinolo, Elizabeth A. Conner, Achim Weber, Mathias Heikenwalder, Valentina M. Factor, Snorri S. Thorgeirsson. Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype. Hepatology

Britta C. Martel, Thomas Litman, Andreas Hald, Hanne Norsgaard, Paola Lovato, Beatrice Dyring-Andersen, Lone Skov, Kristian Thestrup-Pedersen, Søren Skov, Kresten Skak and Lars K. Poulsen. Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis, Experimental Dermatology

CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz. DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia. Nature Genetics

MA Taylor, M Wappett, O Delpuech, H Brown. Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC. Oncogene

Ahrens M, Ammerpohl O, von Schönfels W, Kolarova J, Bens S, Itzel T, Teufel A, Herrmann A, Brosch M, Hinrichsen H, Erhart W, Egberts J, Sipos B, Schreiber S, Häsler R, Stickel F, Becker T, Krawczak M, Röcken C, Siebert R, Schafmayer C, Hampe J. DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery. Cell Metabolism

Julia Merkenschlager, Mickaël J. Ploquin, Urszula Eksmond, Rakieb Andargachew, Georgina Thorborn, Andrew Filby, Marion Pepper, Brian Evavold & George Kassiotis. Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response. Nature Communication

Hongyan Suna, Ran Bib, Peng Liub, Lisa K. Nolanc, Susan J. Lamonta. Combined analysis of primary lymphoid tissues' transcriptomic response to extra-intestinal Escherichia coli (ExPEC) infection. Developmental & Comparative Immunology

F Schmid, Q Wang, M R Huska, M A Andrade-Navarro, M Lemm, I Fichtner, M Dahlmann, D Kobelt, W Walther, J Smith, P M Schlag and U Stein. SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival. Oncogene

2015

Kirsten C. G. Van Dycke, Jeroen L. A. Pennings, Conny T. M. van Oostrom, Linda W. M. van Kerkhof, Harry van Steeg, Gijsbertus T. J. van der Horst, Wendy Rodenburg. Biomarkers for Circadian Rhythm Disruption Independent of Time of Day. PLOS One

Rebekka Petra Diepold, Plasticity genes in gene x environment interactions: expression and inheritance in a mouse model of anxiety. Dissertation Faculty of Biology Ludwig Maximilians University in Munich

Sarah J. Chapplea, Thomas P. Keeleya, Daniela Mastronicolaa, Matthew Arnob, Gema Vizcay-Barrenac, Roland Fleckc, Richard C.M Siowa, Giovanni E. Manna. Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels. Free Radical Biology and Medicine

Daniel Berglind,, Patrick Müller, Mikaela Willmer, Indranil Sinha, Per Tynelius, Erik Näslund, Karin Dahlman-Wright, Finn Rasmussen. Differential methylation in inflammation and type 2 diabetes genes in siblings born before and after maternal bariatric surgery. Obesity

Sandra Mattua, Francesca Fornaria, Luca Quagliataa, Andrea Perra, Maria Maddalena Angioni, Annalisa Petrelli, Silvia Menegon, Andrea Morandi, Paola Chiarugi, Giovanna Maria Ledda-Columbano, Laura Gramantieri, Luigi Terracciano, Silvia Giordanocorrespondenceemail, Amedeo Columbano. The metabolic gene HAO2 is down regulated in mouse, rat and human hepatocellular carcinoma and correlates with metastasis and poor survival. Journal of Hepatology

Julie Prudhomme, Agnès Dubois, Pablo Navarro, Danielle Arnaud, Philip Avner, and Céline Morey. A rapid passage through a two-active-X-chromosome state accompanies the switch of imprinted X-inactivation patterns in mouse trophoblast stem cells. Epigenetics Chromatin

Ute Warnecke-Eberz , Ralf Metzger, Arnulf H. Hölscher, Uta Drebber, Elfriede Bollschweiler. Diagnostic marker signature for esophageal cancer from transcriptome analysis. Tumor Biology

Firoz Shah, César Nicolás, Johan Bentzer, Magnus Ellström, Mark Smits, Francois Rineau, Björn Canbäck, Dimitrios Floudas, Robert Carleer, Gerald Lackner, Jana Braesel, Dirk Hoffmeister, Bernard Henrissat, Dag Ahrén, Tomas Johansson, David S. Hibbett, Francis Martin, Per Persson, Anders Tunlid. Ectomycorrhizal fungi decompose soil organic matter using oxidative mechanisms adapted from saprotrophic ancestors. New Pytologist

Mustimbo E. P. Roberts, Brandon W. Higgs, Philip Brohawn, Fernanda Pilataxi, Xiang Guo, Michael Kuziora, Russell P. Bowler, Wendy I. White. CD4+ T-Cell Profiles and Peripheral Blood Ex-Vivo Responses to T-Cell Directed Stimulation Delineate COPD Phenotypes. Chronic Obstructive Pulmonary Diseases Foundation

James L Reading, Bart Vaes, Caroline Hull, Shereen Sabbah, Thomas Hayday, Nancy S Wang, Anthony DiPiero, Nicholas A Lehman, Jen M Taggart, Fiona Carty, Karen English, Jef Pinxteren, Robert Deans, Anthony E Ting and Timothy IM Tree. Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2The American Society of Gene & Cell Therapy

J Karlsson, A Valind, D Gisselsson. BCOR internal tandem duplication and YWHAE–NUTM2B/E fusion are mutually exclusive events in clear cell sarcoma of the kidney. Genes, Chromosomes and Cancer

C De Leonibus, P Chatelain, C Knight, P Clayton and A Stevens. Effect of summer daylight exposure and genetic background on growth in growth hormone-deficient children. The Pharmacogenomics Journal

Umut Cagina, Olivia F. Duncana,  Ariana P. Gatta, Marc S. Dionneb, Sean T. Sweeneyc, Joseph M. Batemana. Mitochondrial retrograde signaling regulates neuronal function. PNAS

M Pellino. Gene expression analysis and transcriptome evolution in apomicts: a case study in Boechera and Ranunculus. Dissertation submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg

Sumadi Lukman Anwar, Till Krech, Britta Hasemeier, Elisa Schipper, Nora Schweitzer, Arndt Vogel, Hans Kreipe, Ulrich Lehmann. Loss of DNA methylation at imprinted loci is a frequent event in hepatocellular carcinoma and identifies patients with shortened survival. Clinical Epigenetics

Carolina Roya, Pablo Carbonell-Bejerano, Rafael Torres-Pérez, Anna Nebish, Óscar Martínez, Manuel Rey, Rouben Aroutiounian, Javier Ibáñez and José M.Martínez-Zapater.  Developmental, transcriptome, and genetic alterations associated with parthenocarpy in the grapevine seedless somatic variant Corinto bianco. Journal of Experimental Botany, Oxford Journals,

Helene Kretzmer, Stephan H Bernhart, Wei Wang, Andrea Haake, Marc A Weniger, Anke K Bergmann, Matthew J Betts, Enrique Carrillo-de-Santa-Pau, Gero Doose, Jana Gutwein, Julia Richter, Volker Hovestadt, Bingding Huang, Daniel Rico, Frank Jühling, Julia Kolarova, Qianhao Lu, Christian Otto, Rabea Wagener, Judith Arnolds, Birgit Burkhardt, Alexander Claviez, Hans G Drexler, Sonja Eberth, Roland Eils. DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control. Nature Genetics

Anna S. Gerdtsson, Núria Malats, Anna Säll, , Francisco X. Real,, Miquel Porta,  Petter Skoog, Helena Persson,  Christer Wingren, Carl A.K. Borrebaeck. A multicenter trial defining a serum protein signature associated with pancreatic ductal adenocarcinoma. International Journal of Proteomics

Emila Kurbasic, Martin Sjöström, Morten Krogh, Elin Folkesson, Dorthe Grabau, Karin Hansson, Lisa Rydén, Sofia Waldemarson, Peter James Emma Niméus. Changes in glycoprotein expression between primary breast tumour and synchronous lymph node metastases or asynchronous distant metastases. Clinical Proteomics

Maria Wik Markhus , Josef Daniel Rasinger, Marian Kjellevold Malde, Livar Frøyland, Siv Skotheim, Hanne Cecilie Braarud, Kjell Morten Stormark, Ingvild Eide Graff. Docosahexaenoic Acid Status in Pregnancy Determines the Maternal Docosahexaenoic Acid Status 3-, 6-and 12 Months Postpartum. Results from a Longitudinal Observational Study. PLOS One

Armand Valsesia, Pierre Chatelain, Adam Stevens, Valentina Peterkova, Alicia Belgorosky, Mohamad Maghnie, Franco Antoniazzi, Ekaterina Koledova, Jerome Wojcik, Pierre Farmer, Benoit Destenaves and Peter E Clayton. Growth hormone (GH) deficiency status combined with GH receptor polymorphism affects response to GH in children. European Journal of Endocrinology

GJ Walter, V Fleskens, KS Frederiksen, M Rajasekhar. Phenotypic, functional and gene expression profiling of peripheral CD45RA+ and CD45RO+ CD4+ CD25+ CD127low regulatory T cells in rheumatoid arthritis. Arthritis & Rheumatology

Julia K. Seibert, Luca Quagliata, Cristina Quintavalle, Thomas G. Hammond, Luigi Terracciano and Alex Odermatt. A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer. Cancer Medicine

Yu-Chieh Wang,  Jason W. Stein, Candace L. Lynch, Ha T. Tran, Chia-Yao Lee, Ronald Coleman,   Adam Hatch,  Victor G. Antontsev,  Hun S. Chy,  Carmel M. O’Brien,   Shashi K. Murthy, Andrew L. Laslett,  Suzanne E. Peterson and Jeanne F. Loring. Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells. Scientific Reports

A Stucki-Koch, G Hauck, H Kreipe, K Hussein. MicroRNA expression profiles in BCR-ABL-negative primary myelofibrosis with chromosome 7q defects. Journal of Hematopathology

S Coffey, MJA Williams, LV Phillips, GT Jones. Circulating microRNA Profiling Needs Further Refinement Before Clinical Use in Patients With Aortic Stenosis,  Journal of the American Heart Association

R Mesnage, M Arno, M Costanzo, M Malatesta. Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure. Environmental Health

N Ravi. Genetic analysis of Anaplastic Thyroid Cancer. Degree Projects in Molecular Biology. Lund University

JL Deuve, A Bonnet-Garnier, N Beaujean, P Avner. Antagonist Xist and Tsix co-transcription during mouse oogenesis and maternal Xist expression during pre-implantation development calls into question the nature of the maternal imprint on the X chromosome. Epigenetics

NE van der Sligte, FJG Scherpen, A ter Elst, V Guryev. Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Experimental Hematology & Oncology

RD Abeles, CG Antoniades, DL Shawcross, W Khamri. PWE-114 Modulation of non-canonical nfkb pathways may underlie the anti-inflammatory, resolution-like activation of circulating cd14hi monocytes in hyper-acute liver failure. Gut

A Sharma, MA Jamil, N Nuesgen, F Schreiner, L Priebe. DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrationsClinical Epigenetics

MN Møller, S Kirkeby, J Vikeså, FC Nielsen. Expression of histamine receptors in the human endolymphatic sac: the molecular rationale for betahistine use in Menieres disease. European Archives of European Archives of Oto-Rhino-Laryngology

Natalia Torow, Kai Yu, Kasra Hassani, Jenny Freitag, Olga Schulz, Marijana Basic, Anne Brennecke, Tim Sparwasser, Norbert Wagner, André Bleich, Matthias Lochner, Siegfried Weiss, Reinhold Förster, Oliver Pabst & Mathias W. Hornef. Active suppression of intestinal CD4+TCRaß+ T-lymphocyte maturation during the postnatal period. Nature Communications

N Torow, O Dittrich-Breiholz, MW Hornef. Transcriptional profiling of intestinal CD4+ T cells in the neonatal and adult mice. Genomics Data

AK Coussens, RJ Wilkinson, AR Martineau. Phenylbutyrate Is Bacteriostatic against Mycobacterium tuberculosis and Regulates the Macrophage Response to Infection, Synergistically with 25-Hydroxy-Vitamin D3. PLOS Pathogens

Schiøler Schultz. Extracellular matrix proteins as drivers of inflammation in rheumatoid arthritis. Industrial PhD Thesis, University of Copenhagen

Juliane Lippmann, Frederik Gwinner, Camille Rey, Uyanga Tamira, Helen K. W. Lawd, Benno Schwikowski,  Jost Enninga. Bacterial internalization, localization and effectors shape the Epithelial Immune Response during Shigella Infection. Infection and Immunity

V Schlaphoff, K Deterding, S Hardtke, J Hengst, C Falk, B Bremer, MP Manns, M Cornberg and H Wedemeyer. Serum biomarker profile can predict the outcome of acute HCV infection. Journal of Viral Hepatitis

M Wöbse, V Schlaphoff, A Wranke, M Cornberg,CS Falk, C Yur daydin, MP Manns,H Wedemeyer, S Hardtke and HIDIT-2 study-group. Plasma cytokine and chemokine patterns during PEG_IFNa-2a therapy of chronic hepatitis delta.  Journal of Viral Hepatitis

AK Coussens, CE Naude, R Goliath, G Chaplin, Robert J. Wilkinson, Nina G. Jablonski. High-dose vitamin D3 reduces deficiency caused by low UVB exposure and limits HIV-1 replication in urban Southern Africans.  PNAS

JE Simpson, PG Ince, T Minett, FE Matthews, PR Heath. Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology. Neuropathology and Applied Neurobiology

MS Trivedi, EI Chen, D Awad, A Koller, P Patel. Identifying predictors of taxane-induced peripheral neuropathy using shotgun proteomics technologyJournal of Clinical Oncology

S Muhie, R Hammamieh, C Cummings, D Yang, M Jett. Stress-caused anergy of leukocytes towards Staphylococcal enterotoxin B and exposure transcriptome signatures. Genes and Immunity

Y Xiao, S Zijl, L Wang, DC de Groot, MJ van Tol. Identification of the Common Origins of Osteoclasts, Macrophages, and Dendritic Cells in Human Hematopoiesis.  Stem Cell Reports

J Kolarova, I Tangen, S Bens, G Gillessen-Kaesbach. Array-based DNA-methylation analysis in individuals with developmental delay/intellectual disability and normal molecular karyotype.  European Journal of Medical Genetics

SE Khorsandi, A Quaglia, S Salehi, W Jassem.  The microRNA Expression Profile in Donation after Cardiac Death (DCD) Livers and Its Ability to Identify Primary Non Function. PLOS One

S Owusu Sekyere, PV Suneetha, S Hardtke, CS Falk. Type I Interferon Elevates Co-regulatory Receptor Expression on CMV- and EBV-specific CD8 T cells in Chronic Hepatitis CFrontiers in Immunology

A Badr, P Angers, Y Desjardins. Comprehensive analysis of in vitro to ex vitro transition of tissue cultured potato plantlets grown with or without sucrose using metabolic profiling techniquePlant Cell, Tissue and Organ Culture (PCTOC)

Y Wang, P Lavender, J Watson, M Arno, T Lehner. Stress activated DC induce dual homeostatic and inflammasome pathways, which may elicit CD4+ memory T cells and IFN stimulated gene, Journal of Biological Chemistry

SE Bates, R Eisch, A Ling, D Rosing, M Turner. Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data, British Journal of Haematology

S Bustany, J Cahu, P Guardiola, B Sola. Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating the unfolded protein response pathway, BMC Cancer

Z Li, Z Qiao, W Zheng, W Ma. Network Cluster Analysis of Protein–Protein Interaction Network–Identified Biomarker for Type 2 Diabetes, Diabetes Technology & Therapeutics

PM Tørring, MJ Larsen, AD Kjeldsen, LB Ousager. Global Gene Expression Profiling of Telangiectasial Tissue from Patients with Hereditary Haemorrhagic Telangiectasia. Microvascular Research

KP Sørensen, M Thomassen, Q Tan, M Bak, S Cold. ] Long non-coding RNA expression profiles predict metastasis in lymph node-negative breast cancer independently of traditional prognostic markers. Breast Cancer Research

Ufuk Kirik, Karin Hansson, Morten Krogh, Mats Jönsson, Mef Nilbert, Peter James, Ana Carneiro.  Discovery-Based Protein Expression Profiling Identifies Distinct Subgroups and Pathways in Leiomyosarcomas. Molecular Cancer Research

GL Christensen, MLB Jacobsen, A Wendt, IG Mollet. Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium current. Diabetologia

K Hollevoet, E Mason-Osann, F Müller, I Pastan. ] Methylation-associated partial down-regulation of mesothelin causes resistance to anti-mesothelin immunotoxins in a pancreatic cancer cell line. PLoS One,

A Forreryd, H Johansson, AS Albrekt, CAK Borrebaeck. Prediction of Chemical Respiratory Sensitizers Using GARD, a Novel. PLOS One

MN Møller, S Kirkeby, J Vikeså, FC Nielsen. Gene expression demonstrates an immunological capacity of the human endolymphatic sac. The Laryngoscope

AK Östberg, U Dahlgren, YT Sul, CB Johansson. Inflammatory cytokine release is affected by surface morphology and chemistry of titanium implants.  Journal of Materials Science

J Kolarova, O Ammerpohl, J Gutwein, M Welzel, I Baus. In vivo Investigations of the Effect of Short-and Long-Term Recombinant Growth Hormone Treatment on DNA-Methylation in Humans. PLOS One

J Vikeså, AKH Møller, B Kaczkowski, R Borup. Cancers of unknown primary origin (CUP) are characterized by chromosomal instability (CIN) compared to metastasis of know origin. BMC Cancer

KCM Denninger, T Litman, T Marstrand, K Moller. Kinetics of gene expression and bone remodelling in the clinical phase of collagen induced arthritis. Arthritis Research & Therapy

R Stella, G Biancotto, G Arrigoni, F Barrucci, R Angeletti. Proteomics for the detection of indirect markers of steroids treatment in bovine muscle. Proteomics

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YF Wong, PD Wilson, RJ Unwin, JT Norman, M Arno. Retinoic Acid Receptor-Dependent, Cell-Autonomous, Endogenous Retinoic Acid Signaling and Its Target Genes in Mouse Collecting Duct Cells. PLOS ONE

J Carlsson, G Helenius, M Karlsson, O Andrén. Differences in microRNA expression during tumor development in thetransition and peripheral zones of the prostate. oru.diva-portal.org

KH Nord, K Paulsson, S Veerla, J Wejde, O Brosjö. Retained Heterodisomy Is Associated with High Gene Expression in Hyperhaploid Inflammatory Leiomyosarcoma. Neoplasia 

AK Coussens, RJ Wilkinson, Y Hanifa, V Nikolayevskyy. Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment. Proceedings of the National Academy of Sciences of the United States of America,  PNAS

A Sandström, R Andersson, R Segersvärd, ZM Löhr. Serum proteome profiling of pancreatitis using recombinant antibody microarrays reveals disease-associated biomarker.  Proteomics-Clinical

P Sekyrova, J Östblom. Blebbing as a physical force in cancer EMT-Parallels with mitosis. Seminars in Cancer Biology

 K Jääger, S Islam, P Zajac, S Linnarsson. RNA-Seq Analysis Reveals Different Dynamics of Differentiation of Human Dermis-and Adipose-Derived Stromal Stem Cells. PLoS ONE

C Eckmann-Scholz, S Bens, J Kolarova. DNA-Methylation Profiling of Fetal Tissues Reveals Marked Epigenetic Differences between Chorionic and Amniotic Samples. PLoS ONE

PR Young, JG Lashbrooke, E Alexandersson.  The genes and enzymes of the carotenoid biosynthetic pathway in Vitis vinifera L. BMC Genomics

B Sadeghi, H Al-Chaqmaqchi, S Al-Hashmi. Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?  Bone Marrow

J Taneera, S Lang, A Sharma, J Fadista, Y Zhou. A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets. Cell Metabolism

J Gaedcke, M Grade, J Camps, R Sokilde. The rectal cancer microRNAome-microRNA expression in rectal cancer and matched normal mucosa. Clinical Cancer Research

KA Serikawa, S Jacobsen, D Lundsgaard, BA Fox. Detection of gene expression signatures related to underlying disease and treatment in rheumatoid arthritis patients. Modern Rheumatology

MB Lyng, AV Lænkholm, R Søkilde, KH Gravgaard. Global MicroRNA Expression Profiling of High-Risk ER+ Breast Cancers from Patients Receiving Adjuvant Tamoxifen Mono-Therapy: A DBCG Study. PLoS ONE

 C Riou, BP Peixoto, L Roberts, K Ronacher. Effect of Standard Tuberculosis Treatment on Plasma Cytokine Levels in Patients with Active Pulmonary Tuberculosis; PLoS ONE

C B Lajer, E Garnæs, L Friis-Hansen, B Norrild, M H Therkildsen, M Glud, M Rossing, H Lajer, D Svane, L Skotte, L Specht, C Buchwald and F C NielsenThe role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer British Journal of Cancer 106

Felix Haglund, Ming Lu, Vladana Vukojevic, Inga-Lena Nilsson, Adam Andreasson, Mensur Džabic, Robert Bränström, Anders Höög, C. Christofer Juhlin, Catharina LarssonProlactin Receptor in Primary Hyperparathyroidism – Expression, Functionality and Clinical Correlations PLosONE

Harald Osmundsen, Anne-Marthe Jevnaker and Maria A. Landin Deoxyoligonucleotide Microarrays for Gene Expression Profiling in Murine Tooth Germs Odontogenesis

DR de la Bletiere, O Blanchet, P Cornillet-Lefebvre… Routine use of microarray-based gene expression profiling to identify patients with low cytogenetic risk acute myeloid leukemia: accurate results can be obtained even with suboptimal samples BMC Medical Genomics

G Macchia, D Trombetta, E Möller, F Mertens...FOSL1 as a candidate target gene for 11q12 rearrangements in desmoplastic fibroblastoma Laboratory Investigation

Pascale May-Panloup, Véronique Ferré-L'Hôtellier, Catherine Morinière, Charles Marcaillou, Sophie Lemerle, Marie-Claire Malinge, Anne Coutolleau,Nicolas Lucas3,Pascal Reynier, Philippe Descamps, Philippe Guardiola ;Molecular characterization of corona radiata cells from patients with diminished ovarian reserve using microarray and microfluidic-based gene expression profiling Human Reproduction

2011-2010

Ákos Végvária, Melinda Rezeli,Carina Sihlbom, Jari Häkkinen, Elisabet Carlsohn, Johan Malm, Hans Lilja, Thomas Laurell,György Marko-Varga ;Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry Clinical Biochemistry

Jimsgene Sanjmyatav, Thomas Steiner, Heiko Wunderlich, Julia Diegmann, Mieczyslaw Gajda, Kerstin Junker;A Specific Gene Expression Signature Characterizes Metastatic Potential in Clear Cell Renal Cell Carcinoma The Journal of Urology

D Sehic, J Karlsson, B Sandstedt…SIX1 protein expression selectively identifies blastemal elements in Wilms tumor Pediatric Blood & Cancer

Damien Reynaud1, Eric Pietras, Keegan Barry-Holson, Alain Mir, Mikhail Binnewies, Marion Jeanne, Olga Sala-Torra, Jerald P. Radich, Emmanuelle Passegué IL-6 Controls Leukemic Multipotent Progenitor Cell Fate and Contributes to Chronic Myelogenous Leukemia Development Cancer cell 

Debra Rossouw, Dan Jacobson and Florian F. Bauer Transcriptional Regulation and the Diversification of Metabolism in Wine Yeast Strains. Genetics

Killian JK, Bilke S, Davis S, Walker RL, Jaeger E, Killian MS, Waterfall JJ, Bibikova M, Fan JB, Smith WI Jr, Meltzer PS A methyl-deviator epigenotype of estrogen receptor-positive breast carcinoma is associated with malignant biology. Am J Pathol 

D Rossouw, N Jolly, D Jacobson...The effect of scale on gene expression: commercial versus laboratory wine fermentations. Applied Microbiology and Biotechnology

Naiara G Bediaga, Amelia Acha-Sagredo, Isabel Guerra, Amparo Viguri, Carmen Albaina, Irune Ruiz Diaz, Ricardo Rezola, ...DNA methylation epigenotypes in breast cancer molecular subtypes. Breast Cancer Research 

Thibaut Lery, Mario Primicerio, Maria J. Esteban, Magnus Fontes, Yvon Maday, Volker Mehrmann, Goncalo Quadros, Wil Schilders, Andreas Schuppert and Heather Tewkesbury Health & Biology. European Success Stories in Industrial Mathematics

L Kleynhans, N Du Plessis, GF Black, AG Loxton...Medroxyprogesterone Acetate Alters Mycobacterium Bovis BCG-Induced Cytokine Production in Peripheral Blood Mononuclear Cells of Contraceptive Users. PLoSone

Jessica Carlsson, Sabina Davidsson, Gisela Helenius, Mats Karlsson, Zelmina Lubovac, Ove Andrén, Björn Olsson and Karin Klinga-Levan A miRNA expression signature that separates between normal and malignant prostate tissues. Cancer Cell International

Frida Abel, Daniel Dalevi, Maria Nethander, Rebecka Jörnsten, Katleen De Preter, Joëlle Vermeulen, Raymond Stallings, Per Kogner, John Maris and Staffan Nilsson A 6-gene signature identifies four molecular subgroups of neuroblastoma. Cancer Cell International 

H Johansson, M Lindstedt, AS Albrekt... A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests. BMC Genomics

L Fagerberg, S Stromberg, A Elobeid, M Gry... Large-scale Protein Profiling in Human Cell Lines Using Antibody-based Proteomics. Journal of Proteome Research

R Jimbo, J Fernandez-Rodriguez, YT Sul... Principal Component Analysis: A Novel Analysis to Evaluate the Characteristics of Osseointegration of Different Implant Surfaces. Implant Dentistry

M Fontes, C Soneson. The projection score-an evaluation criterion for variable subset selection in PCA visualization. BMC Bioinformatics 

E Möller, JL Hornick, L Magnusson, S Veerla... FUS-CREB3L2/L1–Positive Sarcomas Show a Specific Gene Expression Profile with Upregulation of CD24 and FOXL1 - Clinical Cancer Research

G Styger, D Jacobson... Identifying genes that impact on aroma profiles produced by Saccharomyces cerevisiae and the production of higher alcoholsApplied Microbiology and Biotechnology

CB Johansson, C Gretzer, R Jimbo, I Mattisson... Enhanced implant integration with hierarchically structured implants: a pilot study in rabbits. Clinical Oral Implants Research 

Ole Ammerpohl, Johann Pratschke, Clemens Schafmayer, Andrea Haake, Wladimir Faber, Oliver von Kampen, Mario Brosch, Bence Sipos, Witigo von Schönfels, Katharina Balschun, Christoph Röcken, Alexander Arlt, Bodo Schniewind, Jonas Grauholm, Holger Kalthoff, Peter Neuhaus,,Felix Stickel,,Stefan Schreiber,,Thomas Becker,,Reiner Siebert, Jochen Hampe. Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma. International Journal of Cancer 

Anders Carlsson, Dirk M. Wuttge, Johan Ingvarsson, Anders A. Bengtsson, Gunnar Sturfelt, Carl A. K. Borrebaeck and Christer Wingren. Serum protein profiling of systemic lupus erythematosus and systemic sclerosis using recombinant antibody microarrays.Molecular & Cellular Proteomics

Måns Jergil, Maud Forsberg, Hugh Salter, Kenneth Stockling, Anne-Lee Gustafson, Lennart Dencker and Michael Stigson. Short-Time Gene Expression Response to Valproic Acid and Valproic Acid Analogs in Mouse Embryonic Stem Cells. Toxicological Sciences 

S. Bensa, O. Ammerpohl, J.I. Martin-Suberoa, M. Apparib, J. Richtera, O. Hiortc, R. Wernerc, F.G. Riepeb, R. Sieberta, P.-M. Holterhusb. Androgen Receptor Mutations Are Associated with Altered Epigenomic Programming as Evidenced by HOXA5 Methylation. Sexual Development, online publication 

Joana Heinzelmann, Brenda Henning, Jimsgene Sanjmyatav, Nicole Posorski, Thomas Steiner, Heiko Wunderlich, Mieczyslaw R. Gajda and Kerstin Junker. Specific miRNA signatures are associated with metastasis and poor prognosis in clear cell renal cell carcinoma. World Journal of Urology DOI: 10.1007/s00345-010-0633-4

Linda Dexlin-Mellby, Anna Sandström, Magnus Centlow, Sara Nygren, Stefan R. Hansson, Carl A. K. Borrebaeck, Christer Wingren. Proteomic expression analysis and comparison of protein and mRNA expression profiles in human malignant gliomas. PROTEOMICS – Clinical Applications Volume 4, Issue 10-11, pages 794–807

Järås M, Johnels P, Hansen N, Agerstam H, Tsapogas P, Rissler M, Lassen C,Olofsson T, Bjerrum OW, Richter J, Fioretos T. Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16280-5

Karl Björk, Anita C. Hansson and Wolfgang H. Sommer. Genetic Variation and Brain Gene Expression in Rodent Models of Alcoholism: Implications for medication development. International Review of Neurobiology, Volume 91, pages 129-171

Linda Holmquist Mengelbier, Jenny Karlsson, David Lindgren, Ingrid Öra, Margareth Isaksson, Ildiko Frigyesi, Attila Frigyesi, Johannes Bras||, Bengt Sandstedt, and David Gisselsson. Deletions of 16q in Wilms Tumors Localize to Blastemal-Anaplastic Cells and Are Associatedwith Reduced Expression of the IRXB Renal Tubulogenesis Gene Cluster. The American Journal of Pathology 2010;177:2609-2621

Ulrika Andréasson, Patrik Edén, Carsten Peterson, Carl-Magnus Högerkorp, Mats Jerkeman, Niels Andersen, Mattias Berglund, Christer Sundström, Richard Rosenquist, Carl A.K. Borrebaeck, Sara Ek. Identification of uniquely expressed transcription factors in highly purified B-cell lymphoma samples. American Journal of Hematology. Volume 85, Issue 6, pages 418–425

Linda Dexlin-Mellby, Anna Sandström, Magnus Centlow, Sara Nygren, Stefan R. Hansson, Carl A. K. Borrebaeck, Christer Wingren, Tissue proteome profiling of preeclamptic placenta using recombinant antibody microarrays, PROTEOMICS – Clinical Applications

Magnus Fontes. Statistical and knowledge supported visualization of multivariate data. Submitted to Proceedings from the conference in honour of Gunnar Sparr, Lund , Sweden 8-9 May 2008. Available online here.

Anders Carlsson, Oscar Persson, Johan Ingvarsson, Bengt Widegren, Leif Salford, Carl A. K. Borrebaeck, Christer Wingren, Plasma proteome profiling reveals biomarker patterns associated with prognosis and therapy selection in glioblastoma multiforme patients, PROTEOMICS – Clinical Applications, Volume 4, Issue 6-7, pages 591–602

Gisselsson D, Lindgren D, Mengelbier LH, Ora I, Yeger H. Genetic bottlenecks and the hazardous game of population reduction in cell line based research. Experimental cell research, In Press, Available online 

Julia Richter, Ole Ammerpohl, Jose I Martin-Subero, Manuel Montesinos-Rongen, Marina Bibikova, Eliza Wickham-Garcia, Otmar D Wiestler, Martina Deckert and Reiner Siebert. Array-based DNA methylation profiling of primary lymphomas of the central nervous system. BMC Cancer

Rehannah Borup , Maria Rossing , Ricardo Henao, Yohei Yamamoto, Annelise Krogdahl, Christian Godballe, Ole Winther, Katalin Kiss, Lise Christensen, Estrid Høgdall, Finn Bennedbæk, Finn Cilius Nielsen, Molecular signatures of thyroid follicular neoplasia, Endocrine-Related Cancer 

Astrid Enkelmann, Joana Heinzelmann, Ferdinand von Eggeling, Martina Walter, Alexander Berndt, Heiko Wunderlich and Kerstin Junker, Specific protein and miRNA patterns characterise tumour-associated fibroblasts in bladder cancer, Journal of Cancer Research and Clinical Oncology DOI: 10.1007/s00432-010-0932-6

Malin Lindstedt, Inge Nelissen, Sue Gibbs, Carl Borrebaeck. 2010. Mimicking the immunoregulatory properties of primary dendritic cells in vitro - A rational approach to design a test system. Toxicology Reviews. In press.

Mark J Alston , John Seers , Jay CD Hinton and Sacha Lucchini. BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets. BMC Bioinformatics 

Charlotte Soneson, Henrik Lilljebjörn, Thoas Fioretos, Magnus Fontes.
Multivariate analysis of the relationship between SNP copy number and gene expression in leukemia - Presented at Statistical advances in Genome-scale Data Analysis - Workshop ETH, Ascona 2009

Erik Alexandersson, Jonas Å.H. Danielson, Johan Råde, Vamsi K. Moparthi, Magnus Fontes, Per Kjellbom and Urban Johanson. Transcriptional regulation of aquaporins in accessions of Arabidopsis in response to drought stress, The Plant Journal 

Davidsson Josef; Lilljebjorn Henrik; Andersson Anna; Veerla Srinivas; Heldrup Jesper; Behrendtz Mikael; Fioretos Thoas; Johansson Bertil. The DNA methylome of pediatric acute lymphoblastic leukemia. Human Molecular Genetics

Möller, Emily. EWSR1 and FUS fusion genes in Tumorigenesis. Dissertation at department of Clinical Genetics, Lund Uinversity 

 

Early versions of Gene Expression Explorer have been used in the following references:

Andersson A, Olofsson T, Lindgren D, Nilsson B, Ritz C, Edén P, Lassen C, Råde J, Fontes M, Mörse H, Heldrup J, Behrendtz M, Mitelman F, Höglund M, Johansson B, Fioretos T. 2005. Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations. Proc Natl Acad Sci USA 102:19069-19074.


Andersson A, Ritz C, Lindgren D, Edén P, Lassen C, Heldrup J, Olofsson T, Råde J, Fontes M, Porwit-McDonald A, Behrendtz M, Höglund M, Johansson B, Fioretos T. 2007. Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status. Leukemia 21:1198-1203.

Workshops and books

T Léry, M Primicerio, ... European Success Stories in Industrial Mathematics. Springer

Sylvestre Burgos, Manh Hong Duong, Laura Friis Frølich, Daniel Høyer Iversen, Bogna Pawlowska, Matthias Voigt, Mikalai Zhudro. How to enhance the exploratory power of Qlucore Omics Explorer?. The 23rd ECMI Modelling Week, European Student Workshop on Mathematical Modelling in Industry and Commerce Wroclaw University of Technology, Poland, August 23-30, 2009. Report.