How it works - BioTuring SpatialX
SpatialX is the integrated platform designed for multi-image, multi-technology spatial data (CosMx, Xenium, Visium), offering a host of algorithms and tools for in-context analysis with optimized computation and an updated cell annotation database.
Spatial data
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SpatialX enables the mapping of gene expression profiles to specific spatial locations in tissue, revealing how genes are differentially expressed across distinct regions, cell types, or microenvironments, and identifying spatially variable genes or pathways.
By leveraging cell annotation and spatial transcriptomics data, SpatialX can identify and quantify cell-cell interactions, proximity relationships, and niche-specific cellular compositions, providing insights into tissue architecture and intercellular communication.
SpatialX integrates spatial data with cell annotations to uncover how gene expression and cell type distributions vary across healthy versus diseased tissues, enabling the identification of spatially localized disease mechanisms, biomarkers, or therapeutic targets.
Answer Biologial Questions
How are gene expression patterns spatially organized within tissue?
SpatialX enables the mapping of gene expression profiles to specific spatial locations in tissue, revealing how genes are differentially expressed across distinct regions, cell types, or microenvironments, and identifying spatially variable genes or pathways.
What are the spatial relationships and interactions between cell types in a tissue?
By leveraging cell annotation and spatial transcriptomics data, SpatialX can identify and quantify cell-cell interactions, proximity relationships, and niche-specific cellular compositions, providing insights into tissue architecture and intercellular communication.
How do spatial gene expression and celltype distributions correlate with disease or phenotypic states?
SpatialX integrates spatial data with cell annotations to uncover how gene expression and cell type distributions vary across healthy versus diseased tissues, enabling the identification of spatially localized disease mechanisms, biomarkers, or therapeutic targets.
