DNA methylation

Qlucore Omics Explorer is an easy to use software program well suited for analysis of DNA methylation data.

ANALYZE DNA METHYLATION DATA

DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the best characterized epigenetic mechanism. Research has shown that DNA methylation is manifested in a number of important biological processes and human diseases including cancer.

In Qlucore Omics Explorer a number of different analyses can be done. 

 

Key functionality

  • Check data for outliers by visual inspection using sample Principal Component Analysis (PCA) plots.
  • Perform statistical filtering using ANOVA to enhance results. Unwanted dependencies can be removed with one mouse click.
  • Generate a list of genes that classifies data based on a selection of statistical tests: f-test, t-tests or regression.
  • Present results using for instance heatmaps or PCA plots.

Easy data import

Qlucore Omics Explorer supports many data file formats. Import can be done in several ways, with or without normalization. 

Learn More

Case Studies

Using Qlucore in epigenetics research studies

A range of samples including DNA from patient blood, primary tissue from tumors, and cell lines, are studied.

Cancer Genetics Program at the Hospital for Sick Children (SickKids) in Toronto, Canada.

Read more
RNA-seq case study

RNA-Seq analysis using Qlucore

Performing gene expression analysis based on RNA sequencing data, in Dilated Cardiomyopathy studies.

Stanford University, US

Read more

Analysis of public data using Qlucore

This case study is an example of how the use of public information from multiple sources was used to propose a new classification for glioma cancer.

Beijing Normal University, China

Read more

Interpreting Leukemia proteomics with Qlucore

In this case study Qlucore Omics Explorer is used to generate new ideas and hypotheses through exploration and analysis of proteomics data.

UT MD Anderson Cancer Center in Houston, Texas, US

Read more